Evidence map›Paper›PMID 21274343›Full record

ArticleJournal of clinical research in pediatric endocrinology2010

Fine-needle aspiration biopsy in the diagnosis and follow-up of thyroid nodules in childhood.

Ayça Altıncık, Korcan Demir, Ayhan Abacı, Ece Böber, Atilla Büyükgebiz

Abstract read
In one paragraph

Article in Journal of clinical research in pediatric endocrinology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
  3. Article
  4. Evaluation of Children and Adolescents with Thyroid Nodules: A Single Center ExperienceJournal of clinical research in pediatric endocrinology · 2021
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ayça AltıncıkDokuz Eylül University Faculty of Medicine, Pediatric Endocrinology, İzmir, Turkey. ayca.altincik@deu.edu.tr
Korcan Demir
Ayhan Abacı
Ece Böber
Atilla Büyükgebiz

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the role of fine-needle aspiration biopsy (FNAB) in the management of pediatric thyroid nodules.

methodsResults of 30 FNABs performed in our clinic were retrospectively reviewed. Clinical and surgical follow-up data were obtained from the patient files, and clinical correlation and accuracy of FNAB were evaluated.

resultsThe results of 30 FNABs were reported as benign in 24 (80%), insufficient in 4 (13.3%) patients, malignant in 1 (3.3%), and suspicious in 1 (3.3%) patient. One patient with a FNAB result of malignancy underwent surgery and the histological diagnosis was papillary carcinoma. FNAB was repeated in two of the insufficient biopsies, and reported as benign; in one of these patients, the thyroid nodule disappeared and in one, remained stable at clinical follow-up. Four of the patients with benign FNAB results underwent surgery at clinical follow-up because of an increase in the size of the nodules and one patient was found to have papillary carcinoma. The remaining patients were clinically followed. In this study, the malignancy prevalence was 6.6% in patients with thyroid nodules. There was only one false-negative case.

conclusionFNAB is a reliable diagnostic tool in the management of pediatric thyroid nodules.

Indexed as

AdolescentBiopsy, Fine-NeedleCarcinoma, PapillaryChildDiagnosis, DifferentialFemaleFollow-Up StudiesHumansMaleReproducibility of ResultsRetrospective StudiesSensitivity and SpecificityThyroid GlandThyroid NeoplasmsThyroid NoduleYoung Adultchildrenfine−needle aspiration biopsyFNABthyroid carcinomaThyroid nodules

Identifiers

PMID21274343
PMCPMC3005668

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.