SynthesisEye (London, England)2011
Amblyopia and quality of life: a systematic review.
Synthesis in Eye (London, England), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Short- and long-term outcomes of binocular gaming versus patching in childhood amblyopia: a systematic review and meta-analysis.European journal of pediatrics · 2026Pooled it
- Interventions for improving adherence to amblyopia treatments in children.The Cochrane database of systematic reviews · 2025Pooled it
- Research hotspots and trends of amblyopia treatment from 2015 to 2025: a bibliometric analysis.Frontiers in neuroscience · 2025Pooled it
- Brazilian best practice guidelines for amblyopia diagnosis and management.Arquivos brasileiros de oftalmologia · 2024Guideline
- Amblyopia Preferred Practice Pattern.Ophthalmology · 2023Guideline
- Efficacy of interventions for amblyopia: a systematic review and network meta-analysis.BMC ophthalmology · 2020Pooled it
- Randomised trial of three treatments for amblyopia: Vision therapy and patching, perceptual learning and patching alone.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025Trial
- Randomised controlled trial of video clips and interactive games to improve vision in children with amblyopia using the I-BiT system.The British journal of ophthalmology · 2016Trial
- Binocular treatment of amblyopia using videogames (BRAVO): study protocol for a randomised controlled trial.Trials · 2016Trial
- Impact of COVID-19 on refractive amblyopia risk factors in 5-years-old children: A nationwide cross sectional study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Machine Learning-Based Prediction of Strabismus with and without Amblyopia from Fixation Eye Movements.Ophthalmology science · 2026Article
- Psychometric Performance of Children With Amblyopia During a Tablet-Based Adaptive Visual Acuity Assessment.Investigative ophthalmology & visual science · 2026Article
- Integrating Multi-Task Eye Tracking and Interpretable Machine Learning for High-Accuracy Screening of Amblyopia in Pediatric Populations.Journal of eye movement research · 2026Article
- Binocular versus standard therapy for amblyopia - effect on visual acuity, adherence, and patient or caregiver reported outcomes: protocol for a systematic review.Systematic reviews · 2026Article
- Extending Treatment Duration in Perceptual Learning for Amblyopia.Ophthalmology science · 2026Article
- First-order basis of second-order temporal loss in amblyopia.Journal of translational medicine · 2026Article
- Refractive Error Patterns and the Impact of Cycloplegia in Ametropic Children and Adolescents in Al-Baha, Saudi Arabia.Clinical optometry · 2026Article
- Refractive Risk Factors for Amblyopia in Turkish Preschoolers: A School-Based Vision Screening Study of 1126 Children.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- Obesity and physical activity in children with early vision problems: a secondary analysis of data from the Growing-Up in Ireland study.BMC pediatrics · 2025Article
- Visual acuity, amblyopia and refractive error in preterm children with and without retinopathy of prematurity - Results from the Gutenberg Prematurity Study Young (GPSY).Acta ophthalmologica · 2025Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Amblyopia is a common condition, which can affect up to 5% of the general population. Health-related quality-of-life (HRQoL) implications of amblyopia and/or its treatment have been explored in the literature. A systematic literature search was undertaken during the period of 7-14 May 2010 to identify the HRQoL implications of amblyopia and/or its treatment. A total of 35 papers were included in the literature review. The HRQoL implications of amblyopia related specifically to amblyopia treatment, rather than to the condition itself. These included impact on family life, social interactions, difficulties in undertaking daily activities, as well as feelings and behaviour. The identified studies adopted a number of methodologies. The study populations included children with the condition, parents of children with amblyopia, and adults who had undertaken amblyopia treatment as a child. Some studies developed their own measures of HRQoL, and others determined HRQoL through proxy measures. The reported findings of the HRQoL implications are of importance when considering the management of cases of amblyopia. The issues identified in the literature review are discussed with respect to how HRQoL is measured (treatment compliance vs proxy measures), and whether HRQoL is taken from a child's or a parent's perspective. Changing societal views over glasses and occlusion therapy are also discussed. Further research is required to assess the immediate and long-term effects of amblyopia and/or its treatment on HRQoL using a more standardised approach.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.