Evidence map›Paper›PMID 21272780›Full record

ArticleImmunity2011

Late arrival: recruiting coreceptors to the T cell receptor complex.

P Anton van der Merwe, Shaun-Paul Cordoba

Abstract readComment
PubMed Publisher
In one paragraph

Article in Immunity, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. The kinase occupancy of T cell coreceptors reconsidered.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  2. Article
  3. Coreceptors and TCR Signaling - the Strong and the Weak of It.Frontiers in cell and developmental biology · 2020
    Review
  4. Article
  5. T cell receptor bias for MHC: co-evolution or co-receptors?Cellular and molecular life sciences : CMLS · 2014
    Review
  6. Review
  7. Article
  8. Article
  9. Crystal structure of a complete ternary complex of T-cell receptor, peptide-MHC, and CD4.Proceedings of the National Academy of Sciences of the United States of America · 2012
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

P Anton van der MerweSir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, UK. anton.vandermerwe@path.ox.ac.uk
Shaun-Paul Cordoba

Funding

Medical Research Council G19/31Medical Research Council G9722488Medical Research Council MR/J002011/1
6 · The paper itself

Abstract

In this issue of Immunity, Jiang et al. (2011) provide evidence that the CD8 coreceptor is recruited to the T cell receptor (TCR) complex after initial TCR triggering where it stabilizes the TCR-peptide-major histocompatibility complex interaction.

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.