Evidence map›Paper›PMID 21272016›Full record

ReviewAnnals of the New York Academy of Sciences2011

Pharmacological enhancement of drug cue extinction learning: translational challenges.

K M Kantak, B Á Nic Dhonnchadha

Abstract readReview
In one paragraph

Review in Annals of the New York Academy of Sciences, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

K M KantakLaboratory of Behavioral Neuroscience, Department of Psychology, Boston University, Boston, Massachusetts 02215, USA. kkantak@bu.edu
B Á Nic Dhonnchadha
Boston University · US

Funding

Strategies for Enhancing Extinction of Drug-Seeking BehaviorR01DA024315 · NIDA · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI KANTAK, KATHLEEN M. · 2007 to 2011
$1.9M
NIDA NIH HHS DA024315NIDA NIH HHS R01 DA024315
6 · The paper itself

Abstract

Augmentation of cue exposure (extinction) therapy with cognitive-enhancing pharmacotherapy may constitute a rational strategy for the clinical management of drug relapse. While certain success has been reported for this form of therapy in anxiety disorders, in this paper we highlight several obstacles that may undermine the efficacy of exposure therapy for substance use disorders. We also review translational studies that have evaluated the facilitative effects of the cognitive enhancer D-cycloserine on extinction targeting drug-related cues. Finally, important considerations for the design and implementation of future studies evaluating exposure therapy combined with pharmacotherapy for substance use disorders are discussed.

Indexed as

Cognitive Behavioral TherapyCycloserineExtinction, PsychologicalHumansPsychomotor PerformanceSubstance-Related DisordersTranslational Research, BiomedicalCycloserine

Identifiers

PMID21272016
PMCPMC3064474
OpenAlexW2140021293

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.