Trial reportInternational journal of colorectal disease2011
Transanal endoscopic microsurgery for rectal cancer. Long-term oncologic results.
Trial report in International journal of colorectal disease, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Efficacy and safety of transanal endoscopic microsurgery for early rectal cancer: a meta-analysis.Frontiers in oncology · 2025Pooled it
- Local recurrence after local excision of early rectal cancer: a meta-analysis of completion TME, adjuvant (chemo)radiation, or no additional treatment.The British journal of surgery · 2020Pooled it
- Executive Summary of the American Radium Society Appropriate Use Criteria for Local Excision in Rectal Cancer.International journal of radiation oncology, biology, physics · 2019Guideline
- A multi-centred randomised trial of radical surgery versus adjuvant chemoradiotherapy after local excision for early rectal cancer.BMC cancer · 2016Trial
- Comparing advanced platforms for local excision of rectal lesions.Surgical endoscopy · 2024Article
- Completion Surgery after Non-Curative Local Resection of Early Rectal Cancer.Visceral medicine · 2024Review
- Treatment Options for Distal Rectal Cancer in the Era of Organ Preservation.Current treatment options in oncology · 2024Review
- Transanal full-thickness excision for rectal neoplasm: is it advisable to leave the defect open?Langenbeck's archives of surgery · 2023Article
- Local full-thickness excision for sessile adenoma and cT1-2 rectal cancer: long-term oncological outcome.Langenbeck's archives of surgery · 2022Article
- Transanal Endoscopic Microsurgery with or without Completion Total Mesorectal Excision for T2 and T3 Rectal Carcinoma.Digestive surgery · 2019Observational
- Transanal Minimally Invasive Surgery.Clinics in colon and rectal surgery · 2017Review
- Analysis of local recurrences after transanal endoscopic microsurgery for low risk rectal carcinoma.International journal of colorectal disease · 2017Article
- ACR Appropriateness Criteria® Local Excision in Early Stage Rectal Cancer.American journal of clinical oncology · 2015Review
- Transanal Endoscopic Microsurgery.Clinics in colon and rectal surgery · 2015Review
- Local excision by transanal endoscopic surgery.World journal of gastroenterology · 2015Review
- Outcomes of rectal cancer treatment--influence of age?International journal of colorectal disease · 2014Article
- Transanal endoscopic microsurgery: a review.Canadian journal of surgery. Journal canadien de chirurgie · 2014Review
- Transanal endoscopic surgery using a single access port: a practical tool in the surgeon's toybox.Surgical endoscopy · 2014Article
- The outcome of rectal cancer after early salvage TME following TEM compared with primary TME: a case-matched study.Techniques in coloproctology · 2014Article
- Practice patterns and long-term survival for early-stage rectal cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeLocal excision of malignant rectal tumors remains controversial due to the lack of prospective studies. The principal aim of this paper is to analyze survival and recurrence of patients with rectal cancer who were operated by transanal endoscopic microsurgery with curative intention.
methodsIn 1997, we started a prospective protocol for patients who had T1/T2 rectal tumors: transanal local full-thickness excision was considered curative in T1 low risk (group A); patients with T1 high-risk and T2 low-risk tumors received postoperative radiotherapy (group B). From 1997 to 2006, 88 patients were enrolled. Sixty eight entered the study after the preoperative workup and 20 patients with an initial diagnosis of adenoma after postoperative definitive pathological assessment.
resultsAfter definitive histological findings, 54 patients were to group A, 28 to group B, and 6 had immediate radical surgery. One patient was lost for follow-up. At a mean follow-up of 71 months, 7 (4 from group A and 3 from group B) out of 81 patients recurred. Five-year overall survival was of 94% and cancer-specific survival of 96%.
conclusionsOur data support that transanal endoscopic microsurgery is an adequate treatment for T1 low-risk tumor, and no additional measures are required. For T2 low-risk lesions, our study showed a higher local recurrence rate than that reported after radical surgery but a similar survival outcome.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.