Trial reportNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2011
Neural correlates of response inhibition and cigarette smoking in late adolescence.
Trial report in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed, 2 syntheses or guidelines pooled it, 98 citations in OpenAlex.
- Meta-analysis of aberrant post-error slowing in substance use disorder: implications for behavioral adaptation and self-control.The European journal of neuroscience · 2019Pooled it
- Systematic review of ERP and fMRI studies investigating inhibitory control and error processing in people with substance dependence and behavioural addictions.Journal of psychiatry & neuroscience : JPN · 2014Pooled it
- Intra-individual changes in Stroop-related activations linked to cigarette abstinence in adolescent tobacco smokers: Preliminary findings.Drug and alcohol dependence · 2016Trial
- How left-behind experience moderates the impact of impulsivity on non-suicidal self-injury among Chinese senior high school students: the mediating role of self-control.Frontiers in public health · 2026Article
- Neural Signatures of Cognitive Control Predict Future Adolescent Substance Use Onset and Frequency.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025Article
- Neurogenetic underpinnings of nicotine use severity: Integrating the brain transcriptomes and GWAS variants via network approaches.Psychiatry research · 2024Article
- Unraveling neural complexity: Exploring brain entropy to yield mechanistic insight in neuromodulation therapies for tobacco use disorder.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Altered functional dynamics gradient in schizophrenia with cigarette smoking.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Prepared and reactive inhibition in smokers and non-smokers.Behavioural brain research · 2023Article
- People with tobacco use disorder exhibit more prefrontal activity during preparatory control but reduced anterior cingulate activity during reactive control.Addiction biology · 2022Article
- Effects of substance misuse on inhibitory control in patients with attention-deficit/hyperactivity disorder.Addiction biology · 2022Article
- Altered resting-state electroencephalography microstate characteristics in young male smokers.Frontiers in psychiatry · 2022Article
- Chronic tobacco smoking, impaired reward-based decision-making, and role of insular cortex: A comparison between early-onset smokers and late-onset smokers.Frontiers in psychiatry · 2022Article
- Subtypes of inhibitory and reward activation associated with substance use variation in adolescence: A latent profile analysis of brain imaging data.Cognitive, affective & behavioral neuroscience · 2021Article
- Bidirectional links between adolescent brain function and substance use moderated by cognitive control.Journal of child psychology and psychiatry, and allied disciplines · 2021Article
- Environmental Tobacco Smoke Exposure and Brain Functioning Associated with Smoking Cue-Reactivity and Inhibitory Control in Nonsmoking Adolescents.European addiction research · 2021Article
- Adolescent Substance Use and the Brain: Behavioral, Cognitive and Neuroimaging Correlates.Frontiers in human neuroscience · 2020Article
- Multimodal Neuroimaging Differences in Nicotine Abstinent Smokers Versus Satiated Smokers.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2019Article
- Emotion dysregulation and body mass index: The explanatory role of emotional eating among adult smokers.Eating behaviors · 2019Article
- The relationship between nicotine and psychosis.Therapeutic advances in psychopharmacology · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Smoking is usually initiated in adolescence, and is the leading preventable cause of death in the United States. Little is known, however, about the links between smoking and neurobiological function in adolescent smokers. This study aimed to probe prefrontal cortical function in late adolescent smokers, using a response inhibition task, and to assess possible relationships between inhibition-related brain activity, clinical features of smoking behavior, and exposure to cigarette smoking. Participants in this study were otherwise healthy late adolescent smokers (15-21 years of age; n=25), who reported daily smoking for at least the 6 months before testing, and age- and education-matched nonsmokers (16-21 years of age; n=25), who each reported smoking fewer than five cigarettes in their lifetimes. The subjects performed the Stop-signal Task, while undergoing functional magnetic resonance imaging. There were no significant group differences in prefrontal cortical activity during response inhibition, but the Heaviness of Smoking Index, a measure of smoking behavior and dependence, was negatively related to neural function in cortical regions of the smokers. These findings suggest that smoking can modulate prefrontal cortical function. Given the late development of the prefrontal cortex, which continues through adolescence, it is possible that smoking may influence the trajectory of brain development during this critical developmental period.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.