ArticleClinical and vaccine immunology : CVI2011
Elevated serum levels of CCL17 correlate with increased peripheral blood platelet count in patients with active tuberculosis in China.
Article in Clinical and vaccine immunology : CVI, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 35 citations in OpenAlex.
- Platelet-based biomarkers: A new frontier in inflammation monitoring for respiratory infections.F1000Research · 2025Article
- Distinct inflammatory markers in primary and secondary dengue infection: can cytokines CXCL5, CXCL9, and CCL17 act as surrogate markers?Pathogens and global health · 2024Article
- Evaluation of platelet indices as markers of tuberculosis among children in India.ERJ open research · 2024Article
- Can mean platelet volume be a prognosis predictor in viral infections: An example of Covid-19.Heliyon · 2023Article
- A case ofMultidisciplinary respiratory medicine · 2022Article
- Neutrophils in Tuberculosis: Cell Biology, Cellular Networking and Multitasking in Host Defense.International journal of molecular sciences · 2021Review
- Platelet Activation and the Immune Response to Tuberculosis.Frontiers in immunology · 2021Review
- Mean Platelet Volume (MPV): New Perspectives for an Old Marker in the Course and Prognosis of Inflammatory Conditions.Mediators of inflammation · 2019Review
- Peritransplant Soluble CD30 as a Risk Factor for Slow Kidney Allograft Function, Early Acute Rejection, Worse Long-Term Allograft Function, and Patients' Survival.Disease markers · 2017Article
- Cytokines and Chemokines in Mycobacterium tuberculosis Infection.Microbiology spectrum · 2016Review
- Mean Platelet Volume in Mycobacterium tuberculosis Infection.BioMed research international · 2016Article
- Platelets direct monocyte differentiation into epithelioid-like multinucleated giant foam cells with suppressive capacity upon mycobacterial stimulation.The Journal of infectious diseases · 2014Article
- Mean platelet volume as an inflammation marker in active pulmonary tuberculosis.Multidisciplinary respiratory medicine · 2014Article
- Comparison of platelet count in tuberculosis spine to other spine pathology.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2013Article
- Prominent features of platelet count, plateletcrit, mean platelet volume and platelet distribution width in pulmonary tuberculosis.Multidisciplinary respiratory medicine · 2012Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The serum levels of Th2 markers, including CCL17 (thymus and activation-regulated chemokine [TARC]), CCL22 (macrophage-derived chemokine [MDC]), and soluble CD30, were measured in 101 HIV-negative tuberculosis patients, 103 healthy community controls, and 18 tuberculosis patients in recovery. The levels of CCL17/TARC (249.8 ± 19.91 versus 143.9 ± 10.54, P < 0.0001) and sCD30 (7.78 ± 0.44 versus 4.93 ± 0.23, P < 0.0001) were significantly higher in patients with active tuberculosis than in controls; however, the CCL22/MDC serum level had no statistical difference between the groups (579.9 ± 16.42 versus 556.5 ± 15.29, P = 0.298). The counts of platelet and eosinophil in the peripheral blood of patients with active tuberculosis are significantly increased as well (289.4 ± 8.14 versus 248.3 ± 5.34 [P < 0.0001] and 165.1 ± 14.33 versus 102.5 ± 10.72 [P = 0.0005], respectively), and the platelet counts were positively correlated with serum TARC levels (Pearson r = 0.456, P < 0.0001), which indicates a new source of Th2 bias showing in active TB patients.
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