Trial reportEuropean journal of applied physiology2011
Impact of heat and pollution on oxidative stress and CC16 secretion after 8 km run.
Trial report in European journal of applied physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 51 citations in OpenAlex.
- Continuous exercise induces airway epithelium damage while a matched-intensity and volume intermittent exercise does not.Respiratory research · 2019Trial
- Impairment on Cardiopulmonary Function after Marathon: Role of Exhaled Nitric Oxide.Oxidative medicine and cellular longevity · 2019Trial
- Exercise-Mediated Protection against Air Pollution-Induced Immune Damage: Mechanisms, Challenges, and Future Directions.Biology · 2024Review
- Ozone and childhood respiratory health: A primer for US pediatric providers and a call for a more protective standard.Pediatric pulmonology · 2023Review
- Training in a Hot Environment Fails to Elicit Changes in the Blood Oxidative Stress Response.Journal of human kinetics · 2023Article
- Cold air exposure at - 15 °C induces more airway symptoms and epithelial stress during heavy exercise than rest without aggravated airway constriction.European journal of applied physiology · 2022Article
- Acute effects of short-term exposure to air pollution while being physically active, the potential for modification: A review of the literature.Preventive medicine · 2020Review
- Outdoor Endurance Training with Air Pollutant Exposure Versus Sedentary Lifestyle: A Comparison of Airway Immune Responses.International journal of environmental research and public health · 2019Article
- Update on the Mechanisms of Pulmonary Inflammation and Oxidative Imbalance Induced by Exercise.Oxidative medicine and cellular longevity · 2016Review
- The health effects of exercising in air pollution.Sports medicine (Auckland, N.Z.) · 2014Review
- Respiratory disorders in endurance athletes - how much do they really have to endure?Open access journal of sports medicine · 2014Review
- Transcriptional response of the mussel Mytilus galloprovincialis (Lam.) following exposure to heat stress and copper.PloS one · 2013Article
- Heat acclimation decreased oxidative DNA damage resulting from exposure to high heat in an occupational setting.European journal of applied physiology · 2012Article
- Respiratory health of elite athletes - preventing airway injury: a critical review.British journal of sports medicine · 2012Review
- Clara cell protein in nasal lavage fluid and nasal nitric oxide - biomarkers with anti-inflammatory properties in allergic rhinitis.Clinical and molecular allergy : CMA · 2012Article
- Oxidants, antioxidants, and the beneficial roles of exercise-induced production of reactive species.Oxidative medicine and cellular longevity · 2012Review
- Noninvasive effects measurements for air pollution human studies: methods, analysis, and implications.Journal of exposure science & environmental epidemiologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To investigate the acute effect of a hot, humid and ozone-polluted (O(3)) environment on lung inflammation and oxidative tress of runners performing 8 km time trial run. Using a single-blinded randomized design, 10 male athletes (mean[Formula: see text]= 64.4 mlO(2) kg(-1) min(-1), SD = 4.4) took part in a time trial run in four different environmental conditions: 20°C + 50% relative humidity (rh) (Control); 20°C + 50% rh + 0.10 ppm O(3) (Control + O(3)); 31°C + 70% rh (Heat); 31°C + 70% rh + 0.10 ppm O(3) (Heat + O(3)). Blood samples and nasal lavage were collected post-exercise and analyzed for inflammatory, epithelial damage and oxidative stress markers. Data were analyzed using repeated measures ANOVA with Tukey's post hoc test. A significant increase in CC16 concentration (P < 0.05) and GSH/protein concentration (P < 0.05) in the upper respiratory airways was observed following the 8 km run in the Heat + O(3) trial compared with the control trial. There were no differences in the neutrophil counts between trials. No differences were observed for the other antioxidants analyzed. A hot, humid and ozone-polluted environment (0.1 ppm) elicits an early epithelial damage and antioxidant protection process in the upper respiratory airways of athletes immediately after performing 8 km time trial run.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.