ArticlePLoS biology2011
The importance of synthetic associations will only be resolved empirically.
Article in PLoS biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Trans-ethnic meta-analysis of white blood cell phenotypes.Human molecular genetics · 2014Pooled it
- Potential synthetic associations created by epistasis.Genome biology · 2025Article
- Two decades of association mapping: Insights on disease resistance in major crops.Frontiers in plant science · 2022Review
- Identification of pleiotropy at the gene level between psychiatric disorders and related traits.Translational psychiatry · 2021Article
- The accuracy of LD Score regression as an estimator of confounding and genetic correlations in genome-wide association studies.Genetic epidemiology · 2018Article
- A novel linkage-disequilibrium corrected genomic relationship matrix for SNP-heritability estimation and genomic prediction.Heredity · 2018Article
- Type 2 diabetes: genetic data sharing to advance complex disease research.Nature reviews. Genetics · 2016Review
- The genetic architecture of type 2 diabetes.Nature · 2016Article
- Article
- Kidney disease: new technologies translate mechanisms to cure.The Journal of clinical investigation · 2014Review
- The evolutionary genetics of the genes underlying phenotypic associations for loblolly pine (Pinus taeda, Pinaceae).Genetics · 2013Article
- Evaluating empirical bounds on complex disease genetic architecture.Nature genetics · 2013Article
- Dissecting genome-wide association signals for loss-of-function phenotypes in sorghum flavonoid pigmentation traits.G3 (Bethesda, Md.) · 2013Article
- Low-density lipoprotein receptor mutations generate synthetic genome-wide associations.European journal of human genetics : EJHG · 2013Article
- Windfalls and pitfalls: Applications of population genetics to the search for disease genes.Evolution, medicine, and public health · 2013Article
- Rare genetic variants and treatment response: sample size and analysis issues.Statistics in medicine · 2012Article
- Interpreting noncoding genetic variation in complex traits and human disease.Nature biotechnology · 2012Review
- Clinical review: Genome-wide association studies of skeletal phenotypes: what we have learned and where we are headed.The Journal of clinical endocrinology and metabolism · 2012Review
- Prioritizing genetic variants for causality on the basis of preferential linkage disequilibrium.American journal of human genetics · 2012Article
- Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases.Human molecular genetics · 2012Article
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.