ArticleJournal of acquired immune deficiency syndromes (1999)2011
Predictors of successful early infant diagnosis of HIV in a rural district hospital in Zambézia, Mozambique.
Article in Journal of acquired immune deficiency syndromes (1999), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 5 of them syntheses that pooled it.
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Who cites it
70 citing papers in PubMed, 5 syntheses or guidelines pooled it, 105 citations in OpenAlex.
- Examining barriers to antiretroviral therapy initiation in infants living with HIV in sub-Saharan Africa despite the availability of point-of-care diagnostic testing: a narrative systematic review.Journal of the International AIDS Society · 2024Pooled it
- Pooled it
- Impact of geographic and transportation-related barriers on HIV outcomes in sub-Saharan Africa: a systematic review.AIDS and behavior · 2014Pooled it
- The magnitude of loss to follow-up of HIV-exposed infants along the prevention of mother-to-child HIV transmission continuum of care: a systematic review and meta-analysis.AIDS (London, England) · 2013Pooled it
- Missed opportunities to prevent mother-to-child-transmission: systematic review and meta-analysis.AIDS (London, England) · 2012Pooled it
- Factors influencing the delivery and uptake of early infant diagnosis of HIV services in Greater Accra, Ghana: A qualitative study.PloS one · 2021Trial
- Maternal Engagement in HIV Care and Antiretroviral Therapy Uptake Among Children Living With HIV.JAMA network open · 2026Article
- Article
- A scoping review on HIV early infant diagnosis among HIV exposed infants, ART use and adherence in Tanzania.BMC infectious diseases · 2023Article
- Access, timeliness and retention for HIV testing under early infant diagnosis (EID) program, India.Scientific reports · 2023Article
- Early infant diagnosis testing for HIV in a hard-to-reach fishing community in Uganda.PloS one · 2023Article
- Association between service readiness and PMTCT cascade effectiveness: a 2018 cross-sectional analysis from Manica province, Mozambique.BMC health services research · 2022Article
- Long-Distance Travel for HIV-Related Care-Burden or Choice?: A Mixed Methods Study in Tanzania.AIDS and behavior · 2021Article
- Factors associated with the timely uptake of initial HIV virologic test among HIV-exposed infants attending clinics within a faith-based HIV program in Kenya; a cross-sectional study.BMC public health · 2021Article
- Correlates of uptake of HIV testing among children and young adolescents in Akwa-Ibom state, Nigeria: a secondary data analysis of the Akwa-Ibom aids indicator survey, 2017.BMC pediatrics · 2021Article
- Mortality and Loss to Follow-Up Among HIV-Exposed Infants After Option BFrontiers in pediatrics · 2021Article
- Implementation of an active case management network to identify HIV-positive infants and accelerate the initiation of antiretroviral therapy, Thailand 2015 to 2018.Journal of the International AIDS Society · 2020Article
- Programmatic evaluation of feasibility and efficiency of at birth and 6-week, point of care HIV testing in Kenyan infant.PloS one · 2020Article
- Correlates and determinants of Early Infant Diagnosis outcomes in North-Central Nigeria.AIDS research and therapy · 2019Article
- Rates and Predictors of HIV-Exposed Infants Lost to Follow-Up During Early Infant Diagnosis Services in Kenya.AIDS patient care and STDs · 2019Article
10 more citing papers are in PubMed but not listed here.
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundA key challenge inhibiting the timely initiation of pediatric antiretroviral treatment is the loss to follow-up of mothers and their infants between the time of mothers' HIV diagnoses in pregnancy and return after delivery for early infant diagnosis of HIV. We sought to identify barriers to follow-up of HIV-exposed infants in rural Zambézia Province, Mozambique.
methodsWe determined follow-up rates for early infant diagnosis and age at first test in a retrospective cohort of 443 HIV-infected mothers and their infants. Multivariable logistic regression models were used to identify factors associated with successful follow-up.
resultsOf the 443 mother-infant pairs, 217 (49%) mothers enrolled in the adult HIV care clinic, and only 110 (25%) infants were brought for early infant diagnosis. The predictors of follow-up for early infant diagnosis were larger household size (odds ratio [OR], 1.29; 95% confidence interval [CI], 1.09-1.53), independent maternal source of income (OR, 10.8; 95% CI, 3.42-34.0), greater distance from the hospital (OR, 2.14; 95% CI, 1.01-4.51), and maternal receipt of antiretroviral therapy (OR, 3.15; 95% CI, 1.02-9.73). The median age at first test among 105 infants was 5 months (interquartile range, 2-7); 16% of the tested infants were infected.
conclusionsThree of four HIV-infected women in rural Mozambique did not bring their children for early infant HIV diagnosis. Maternal receipt of antiretroviral therapy has favorable implications for maternal health that will increase the likelihood of early infant diagnosis. We are working with local health authorities to improve the linkage of HIV-infected women to HIV care to maximize early infant diagnosis and care.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.