ArticleGenome biology and evolution2011
Massive genomic decay in Serratia symbiotica, a recently evolved symbiont of aphids.
Article in Genome biology and evolution, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 127 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
127 citing papers in PubMed, 209 citations in OpenAlex.
- Transcriptional Reshaping of Bacteriocytes in the Aphid-Insects · 2026Article
- The transcriptional and translational outcomes for pseudogenes in bacterial endosymbionts.Molecular biology and evolution · 2026Article
- Comparative genomics and metabolic model analysis of primary and secondary endosymbionts present in different species of whitefly.Journal of insect science (Online) · 2026Article
- The reduced genome of Candidatus Portiera sp. in Bemisia afer: evolutionary trajectories and functional implications.BMC genomics · 2026Article
- Article
- Ecological Mercenaries: Why Aphids Remain Premier Models for the Study of Ecological Symbiosis.Insects · 2025Review
- Article
- Adaptive pangenomic remodeling in the Azolla cyanobiont amid a transient microbiome.The ISME journal · 2025Article
- Infected connections: Unraveling the impact of a bacterial symbiont on ant-aphid partnership.PloS one · 2025Article
- Comparative genomic analysis of symbiotic and free-livingApplied and environmental microbiology · 2024Article
- Coordination of host and endosymbiont gene expression governs endosymbiont growth and elimination in the cereal weevil Sitophilus spp.Microbiome · 2023Article
- Complex host/symbiont integration of a multi-partner symbiotic system in the eusocial aphidiScience · 2022Article
- The Di-Symbiotic Systems in the AphidsMicroorganisms · 2022Article
- Pseudofinder: Detection of Pseudogenes in Prokaryotic Genomes.Molecular biology and evolution · 2022Article
- Ecology and evolution of chlamydial symbionts of arthropods.ISME communications · 2022Article
- Divergent paths in the evolutionary history of maternally transmitted clam symbionts.Proceedings. Biological sciences · 2022Article
- Transitional genomes and nutritional role reversals identified for dual symbionts of adelgids (Aphidoidea: Adelgidae).The ISME journal · 2022Article
- Spatial distribution and community structure of microbiota associated with cowpea aphid (3 Biotech · 2022Article
- Microbiome analyses of 12 psyllid species of the family Psyllidae identified various bacteria including Fukatsuia and Serratia symbiotica, known as secondary symbionts of aphids.BMC microbiology · 2022Article
- Evolutionarily recent dual obligatory symbiosis among adelgids indicates a transition between fungus- and insect-associated lifestyles.The ISME journal · 2022Article
67 more citing papers are in PubMed but not listed here.
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
All vertically transmitted bacterial symbionts undergo a process of genome reduction over time, resulting in tiny, gene-dense genomes. Comparison of genomes of ancient bacterial symbionts gives only limited information about the early stages in the transition from a free-living to symbiotic lifestyle because many changes become obscured over time. Here, we present the genome sequence for the recently evolved aphid symbiont Serratia symbiotica. The S. symbiotica genome exhibits several of the hallmarks of genome evolution observed in more ancient symbionts, including elevated rates of evolution and reduction in genome size. The genome also shows evidence for massive genomic decay compared with free-living relatives in the same genus of bacteria, including large deletions, many pseudogenes, and a slew of rearrangements, perhaps promoted by mobile DNA. Annotation of pseudogenes allowed examination of the past and current metabolic capabilities of S. symbiotica and revealed a somewhat random process of gene inactivation with respect to function. Analysis of mutational patterns showed that deletions are more common in neutral DNA. The S. symbiotica genome provides a rare opportunity to study genome evolution in a recently derived heritable symbiont.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.