ArticleMathematical medicine and biology : a journal of the IMA2012
Computational models of VEGF-associated angiogenic processes in cancer.
Article in Mathematical medicine and biology : a journal of the IMA, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 28 citations in OpenAlex.
- Predicting organoid morphology through a phase field model: Insights into cell division and lumenal pressure.PLoS computational biology · 2025Article
- Review
- Effects of endothelial cell proliferation and migration rates in a computational model of sprouting angiogenesis.Scientific reports · 2016Article
- Systems biology of the microvasculature.Integrative biology : quantitative biosciences from nano to macro · 2015Review
- A systems biology view of blood vessel growth and remodelling.Journal of cellular and molecular medicine · 2014Review
- The Proteome of a Healthy Human during Physical Activity under Extreme Conditions.Acta naturae · 2014Article
- Optimal chemotherapy for leukemia: a model-based strategy for individualized treatment.PloS one · 2014Article
- Applying systems biology methods to the study of human physiology in extreme environments.Extreme physiology & medicine · 2013Article
- Manipulating the microvasculature and its microenvironment.Critical reviews in biomedical engineering · 2013Review
- Compartment model predicts VEGF secretion and investigates the effects of VEGF trap in tumor-bearing mice.Frontiers in oncology · 2013Article
- Multiscale imaging and computational modeling of blood flow in the tumor vasculature.Annals of biomedical engineering · 2012Review
- Integration of experimental and computational approaches to sprouting angiogenesis.Current opinion in hematology · 2012Review
- Pharmacokinetics and pharmacodynamics of VEGF-neutralizing antibodies.BMC systems biology · 2011Article
- A two-compartment model of VEGF distribution in the mouse.PloS one · 2011Article
- Stimulus-responsive ultrasound contrast agents for clinical imaging: motivations, demonstrations, and future directions.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
Tumour angiogenesis allows a growing mass of cancer cells to overcome oxygen diffusion limitation and to increase cell survival. The growth of capillaries from pre-existing blood vessels is the result of numerous signalling cascades involving different molecules and of cellular events involving multiple cell and tissue types. Computational models offer insight into the mechanisms governing angiogenesis and provide quantitative information on parameters difficult to assess by experiments alone. In this article, we summarize results from computational models of tumour angiogenic processes with a focus on the molecular-detailed vascular endothelial growth factor-associated models that have been developed in our laboratory, spanning multiple scales from the molecular to whole body.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.