ArticleHuman reproduction (Oxford, England)2011
Do polymorphic variants of chromosomes affect the outcome of in vitro fertilization and embryo transfer treatment?
Article in Human reproduction (Oxford, England), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
31 citing papers in PubMed, 97 citations in OpenAlex.
- Trial
- Effect of pericentric inversion of chromosome 9 on reproductive outcomes in assisted reproductive technology: a propensity score-matched cohort study.Frontiers in endocrinology · 2026Article
- Impact of chromosomal polymorphisms on pregnancy outcomes after in vitro fertilization or intracytoplasmic sperm injection: A systematic review and meta-analysis.Pakistan journal of medical sciences · 2025Review
- The Potential Role of Chromosomal Polymorphic Variations Attributed to Male Infertility: A Retrospective Cohort Study.Journal of reproduction & infertility · 2025Article
- Karyotypic analysis of 62,587 Han Chinese infertile couples undergoing assisted reproductive technology treatments: insights into chromosomal variations.BMC genomics · 2025Observational
- Application of Chromosomal Karyotype Analysis Combined With Chromosomal Microarray Analysis in the Amniotic Fluid of Advanced Maternal Age.Journal of clinical laboratory analysis · 2025Article
- The Value of Parental Karyotyping in Recurrent Pregnancy Loss Lies in Individual Risk Assessments.Medicina (Kaunas, Lithuania) · 2024Article
- Diverse impacts of female chromosomal polymorphisms on assisted reproduction outcomes: a retrospective cohort study.BMC pregnancy and childbirth · 2024Article
- The Progress of Research on Genetic Factors of Recurrent Pregnancy Loss.Genetics research · 2023Review
- Chromosomal polymorphisms have no negative effect on reproductive outcomes after IVF/ICSI-ET/FET.Scientific reports · 2022Article
- Impact of parental chromosomal polymorphisms on the incidence of congenital anomalies and perinatal complications in a cohort of newborns conceived after ICSI + PGT-A.Reproductive biology and endocrinology : RB&E · 2022Article
- Chromosomal polymorphisms in assisted reproduction: an analysis of 942 cycles.Reproduction & fertility · 2022Article
- Segmental duplications and their variation in a complete human genome.Science (New York, N.Y.) · 2022Article
- Analysis of Aneuploidy Rate and Pregnancy Outcomes in Unexplained Recurrent Pregnancy Loss Couples With Chromosome Polymorphism After PGT-A.Frontiers in medicine · 2022Article
- Analysis of parental abnormal chromosomal karyotype and subsequent live births in Chinese couples with recurrent pregnancy loss.Scientific reports · 2021Article
- Chromosomal polymorphisms associated with reproductive outcomes after IVF-ET.Journal of assisted reproduction and genetics · 2020Article
- [Chromosomal polymorphisms are associated with blastomere multinucleation in IVF/ICSI cycles].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2020Article
- Effects of chromosome 9 inversion on IVF/ICSI: A 7-year retrospective cohort study.Molecular genetics & genomic medicine · 2019Article
- C-banding and AgNOR-staining were still effective complementary methods to indentify chromosomal heteromorphisms and some structural abnormalities in prenatal diagnosis.Molecular cytogenetics · 2019Article
- Chromosomal polymorphisms are independently associated with multinucleated embryo formation.Journal of assisted reproduction and genetics · 2018Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND The aim of this study was to investigate the effect of chromosomal polymorphic variations on the outcome of IVF and embryo transfer (IVF-embryo transfer) treatment for infertile couples. METHODS During the period from October 2006 to December 2009, 1978 infertile couples who had received their first IVF-embryo transfer treatment cycle in our hospital were selected for this retrospective study, and the frequency of chromosomal polymorphic variations was calculated. From these, 1671 couples were selected and divided into three groups: 1402 couples with normal chromosomes (Group 1/control group), 82 couples with chromosomal polymorphic variations in only females (Group 2) and 187 couples with chromosomal polymorphic variations in only males (Group 3). The clinical pregnancy rates (CPR), early miscarriage rates and ongoing pregnancy rates after IVF-embryo transfer treatment were compared. RESULTS There were no statistically significant differences among the three groups in implantation rates (29.37% in the control group, 29.70% in Group 2 and 31.41% in Group 3, P > 0.05) and CPR (45.86, 46.34 and 51.87%, respectively, P > 0.05). Although there was a trend toward higher first trimester pregnancy loss rates in Group 3 (male chromosomal polymorphic variations), but not in Group 2, compared with normal karyotype couples (10.31 versus 6.84%), the difference did not reach significance (P > 0.05). CONCLUSIONS Chromosomal polymorphic variations appear to have no adverse effects on the outcome of IVF-embryo transfer treatment.
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