ArticleInternational journal of health geographics2011
Lung cancer risk and pollution in an industrial region of Northern Spain: a hospital-based case-control study.
Article in International journal of health geographics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Elevated matrix metalloproteinase-7 expression promotes metastasis in human lung carcinoma.World journal of surgical oncology · 2015Pooled it
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- Spatial distribution of hospital admissions for asthma in the central area of Asturias, Northern Spain.BMC public health · 2023Article
- Methodological approaches to the study of cancer risk in the vicinity of pollution sources: the experience of a population-based case-control study of childhood cancer.International journal of health geographics · 2019Article
- Health effects of environmental pollution in population living near industrial complex areas in Korea.Environmental health and toxicology · 2018Article
- Lung Cancer Risk and Residential Exposure to Air Pollution: A Korean Population-Based Case-Control Study.Yonsei medical journal · 2017Article
- Residence in Proximity of a Coal-Oil-Fired Thermal Power Plant and Risk of Lung and Bladder Cancer in North-Eastern Italy. A Population-Based Study: 1995-2009.International journal of environmental research and public health · 2017Article
- Correlation analysis of lung cancer and urban spatial factor: based on survey in Shanghai.Journal of thoracic disease · 2016Article
- Platelet VEGF and serum TGF-β1 levels predict chemotherapy response in non-small cell lung cancer patients.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2015Article
- Particulate matter air pollution exposure, distance to road, and incident lung cancer in the nurses' health study cohort.Environmental health perspectives · 2014Article
- Lung cancer correlates in Lebanese adults: a pilot case--control study.Journal of epidemiology and global health · 2013Article
- A review of the epidemiological methods used to investigate the health impacts of air pollution around major industrial areas.Journal of environmental and public health · 2013Review
- Association of p21 Ser31Arg and p53 Arg72Pro polymorphisms with lung cancer risk in CAPUA study.Lung Cancer (Auckland, N.Z.) · 2012Article
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7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundAsturias, an Autonomous Region in Northern Spain with a large industrial area, registers high lung cancer incidence and mortality. While this excess risk of lung cancer might be partially attributable to smoking habit and occupational exposure, the role of industrial and urban pollution also needs to be assessed. The objective was to ascertain the possible effect of air pollution, both urban and industrial, on lung cancer risk in Asturias.
methodsThis was a hospital-based case-control study covering 626 lung cancer patients and 626 controls recruited in Asturias and matched by ethnicity, hospital, age, and sex. Distances from the respective participants' residential locations to industrial facilities and city centers were computed. Using logistic regression, odds ratios (ORs) and 95% confidence intervals (95%CIs) for categories of distance to urban and industrial pollution sources were calculated, with adjustment for sex, age, hospital area, tobacco consumption, family history of cancer, and occupation.
resultsWhereas individuals living near industries displayed an excess risk of lung cancer (OR = 1.49; 95%CI = 0.93-2.39), which attained statistical significance for small cell carcinomas (OR = 2.23; 95%CI = 1.01-4.92), residents in urban areas showed a statistically significant increased risk for adenocarcinoma (OR = 1.92; 95%CI = 1.09-3.38). In the Gijon health area, residents in the urban area registered a statistically significant increased risk of lung cancer (OR = 2.17; 95%CI = 1.25-3.76), whereas in the Aviles health area, no differences in risk were found by area of exposure.
conclusionsThis study provides further evidence that air pollution is a moderate risk factor for lung cancer.
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