ArticleExpert review of endocrinology & metabolism2010
Anterior pituitary adenomas: inherited syndromes, novel genes and molecular pathways.
Article in Expert review of endocrinology & metabolism, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 46 citations in OpenAlex.
- Pituitary Tumorigenesis-Implications for Management.Medicina (Kaunas, Lithuania) · 2023Review
- Renal transplantation in gigantism: A case report.World journal of transplantation · 2022Article
- ST8SIA6-AS1 Promotes the Epithelial-to-Mesenchymal Transition and Angiogenesis of Pituitary Adenoma.Journal of oncology · 2022Article
- Pituitary Adenoma in Pediatric and Adolescent Populations.Journal of neuropathology and experimental neurology · 2019Article
- An update on the genetics of benign pituitary adenomas in children and adolescents.Current opinion in endocrine and metabolic research · 2018Article
- Article
- AIP mutations in young patients with acromegaly and the Tampico Giant: the Mexican experience.Endocrine · 2016Article
- A giant? Think of genetics: growth hormone-producing adenomas in the young are almost always the result of genetic defects.Endocrine · 2015Article
- Clinical and genetic characterization of pituitary gigantism: an international collaborative study in 208 patients.Endocrine-related cancer · 2015Article
- Genetic mutations in sporadic pituitary adenomas--what to screen for?Nature reviews. Endocrinology · 2015Review
- Gigantism and acromegaly due to Xq26 microduplications and GPR101 mutation.The New England journal of medicine · 2014Article
- Carney complex and McCune Albright syndrome: an overview of clinical manifestations and human molecular genetics.Molecular and cellular endocrinology · 2014Review
- Familial isolated pituitary adenoma caused by a Aip gene mutation not described before in a family context.Endocrine pathology · 2013Article
- Familial isolated pituitary adenomas (FIPA) and the pituitary adenoma predisposition due to mutations in the aryl hydrocarbon receptor interacting protein (AIP) gene.Endocrine reviews · 2013Review
- Familial isolated pituitary adenomas: an emerging clinical entity.Journal of endocrinological investigation · 2012Review
- Lack of mutations in the gene coding for the hGR (NR3C1) in a pediatric patient with ACTH-secreting pituitary adenoma, absence of stigmata of Cushing's syndrome and unusual histologic features.Journal of pediatric endocrinology & metabolism : JPEM · 2012Article
- Genetics of gigantism and acromegaly.Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research SocietyReview
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Pituitary adenomas are common tumors. Although rarely malignant, pituitary adenomas cause significant morbidity due to mass effects and/or hormonal hypo- and/or hyper-secretion. Molecular understanding of pituitary adenoma formation is essential for the development of medical therapies and the treatment of post-operative recurrences. In general, mutations in genes involved in genetic syndromes associated with pituitary tumors are not a common finding in sporadic lesions. By contrast, multiple endocrine neoplasia type 1 (MEN-1) and aryl hydrocarbon receptor-interacting protein (AIP) mutations may be more frequent among specific subgroups of patients, such as children and young adults, with growth hormone-producing adenomas. In this article, we present the most recent data on the molecular pathogenesis of pituitary adenomas and discuss some of the most recent findings from our laboratory. Guidelines for genetic screening and clinical counseling of patients with pituitary tumors are provided.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.