ReviewPediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies2011
Hemodynamic monitoring by transpulmonary thermodilution and pulse contour analysis in critically ill children.
Review in Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02490176 (Effects of Liraglutide on Hemodynamic Parameters in Patients With Heart Failure), which is not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Liraglutide on Hemodynamic Parameters in Patients With Heart Failure
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.
- Surviving Sepsis Campaign International Guidelines for the Management of Sepsis and Septic Shock in Children 2026.Intensive care medicine · 2026Pooled it
- Propranolol Reduces Cardiac Index But does not Adversely Affect Peripheral Perfusion in Severely Burned Children.Shock (Augusta, Ga.) · 2016Trial
- Septic Cardiomyopathy: Age-Dependent Physiology and Hemodynamic Aspects-A Narrative Review.Children (Basel, Switzerland) · 2026Review
- Use of COJournal of cardiovascular development and disease · 2023Review
- Automatic Prediction of Paediatric Cardiac Output From Echocardiograms Using Deep Learning Models.CJC pediatric and congenital heart disease · 2023Article
- Lung Ultrasound versus Chest X-Ray for the Detection of Fluid Overload in Critically Ill Children: A Systematic Review.Journal of pediatric intensive care · 2022Review
- [Hemodynamic monitoring in pediatric anesthesia].Die Anaesthesiologie · 2022Review
- Safety aspects of the PiCCO thermodilution-cardiac output catheter during magnetic resonance imaging at 3 Tesla.Journal of clinical monitoring and computing · 2022Article
- Volumetric Monitoring and Extravascular Lung Water in Perioperative Setting and Critically Ill.Turkish journal of anaesthesiology and reanimation · 2021Article
- Recommendations for hemodynamic monitoring for critically ill children-expert consensus statement issued by the cardiovascular dynamics section of the European Society of Paediatric and Neonatal Intensive Care (ESPNIC).Critical care (London, England) · 2020Article
- Comparison of stroke volumes assessed by three-dimensional echocardiography and transpulmonary thermodilution in a pediatric animal model.Journal of clinical monitoring and computing · 2017Article
- Comparison between pressure-recording analytical method (PRAM) and femoral arterial thermodilution method (FATD) cardiac output monitoring in an infant animal model of cardiac arrest.Intensive care medicine experimental · 2016Article
- Transpulmonary Thermodilution Versus Transthoracic Echocardiography for Cardiac Output Measurements in Severely Burned Children.Shock (Augusta, Ga.) · 2016Article
- Hemodynamic volumetry using transpulmonary ultrasound dilution (TPUD) technology in a neonatal animal model.Journal of clinical monitoring and computing · 2015Article
- Combined Cerebral and Renal Near-Infrared Spectroscopy After Congenital Heart Surgery.Pediatric cardiology · 2015Article
- Trending ability and limitations of transpulmonary thermodilution and pulse contour cardiac output measurement in cats as a model for pediatric patients.Journal of clinical monitoring and computing · 2015Article
- Measurement of cardiac output in children by pressure-recording analytical method.Pediatric cardiology · 2015Article
- Comparison of transpulmonary thermodilution and ultrasound dilution technique: novel insights into volumetric parameters from an animal model.Pediatric cardiology · 2012Article
- Non-invasive cardiac output and oxygen delivery measurement in an infant with critical anemia.Journal of clinical monitoring and computing · 2011Article
- Transpulmonary thermodilution in a pediatric patient with an intracardiac left-to-right shunt.Journal of clinical monitoring and computing · 2011Article
Corrections and comments
- Commented on by
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo summarize the physiologic principles underlying the hemodynamic monitoring using the PiCCO device (Pulsion, Munich, Germany) incorporating the transpulmonary thermodilution technique, the pulse contour cardiac output, and estimation of the arterial pressure variation method. Analysis and review of the current literature.
designA MEDLINE-based literature search using the key words transpulmonary thermodilution, pulse contour analysis, cardiac output, animal models, and child. MEASUREMENTS AND MAIN
resultsThe bias and precision of cardiac output measured by transpulmonary thermodilution are reliable. The reproducibility for repeated measurements is approximately 5% and the percentage error is approximately 15%. Transpulmonary thermodilution may adequately track changes in cardiac output in animals submitted to hypovolemic conditions and during volume loading. Conversely, data from experimental and clinical studies suggest that continuous monitoring of cardiac output using pulse contour analysis requires careful interpretation because periodic recalibration with transpulmonary thermodilution is necessary. Transpulmonary thermodilution-derived static indicator of cardiac preload (global end-diastolic volume, intrathoracic blood volume) may be more sensitive than conventional measurements of vascular filling pressure. However, the value of stroke volume variation or pulse pressure variation have not been evaluated in pediatric patients. Further studies are needed to determine whether theoretical assumptions underlying the measurement of extravascular lung water are valid in children.
conclusionsThe PiCCO device may be a useful adjunct for hemodynamic monitoring in critically ill children. Further studies are needed to clarify the reliability and clinical value of pulse contour method and extravascular lung water measurement.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.