Evidence map›Paper›PMID 21263171›Full record

ArticlePhysics in medicine and biology2011

Computer-aided detection of early interstitial lung diseases using low-dose CT images.

Sang Cheol Park, Jun Tan, Xingwei Wang, Dror Lederman, Joseph K Leader, Soo Hyung Kim, Bin Zheng

Abstract read
In one paragraph

Article in Physics in medicine and biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. An Effective Approach for Automated Lung Node Detection using CT Scans.Journal of biomedical physics & engineering · 2022
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. [Interstitial lung disease associated with lung cancer treatment].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2013
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sang Cheol ParkSchool of Electronics and Computer Engineering, Chonnam National University, Gwangju, Korea.
Jun Tan
Xingwei Wang
Dror Lederman
Joseph K Leader
Soo Hyung Kim
Bin Zheng

Funding

Peripheral Markers of Phenotypic Heterogeneity in COPDP50HL084948 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SCIURBA, FRANK · 2007 to 2012
$12.8M
Computerized Classification of COPD and Contributing ComponentsR01HL085096 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LEADER, JOSEPH K · 2007 to 2010
$1.3M
NHLBI NIH HHS P50 HL084948NHLBI NIH HHS R01 HL085096
6 · The paper itself

Abstract

This study aims to develop a new computer-aided detection (CAD) scheme to detect early interstitial lung disease (ILD) using low-dose computed tomography (CT) examinations. The CAD scheme classifies each pixel depicted on the segmented lung areas into positive or negative groups for ILD using a mesh-grid-based region growth method and a multi-feature-based artificial neural network (ANN). A genetic algorithm was applied to select optimal image features and the ANN structure. In testing each CT examination, only pixels selected by the mesh-grid region growth method were analyzed and classified by the ANN to improve computational efficiency. All unselected pixels were classified as negative for ILD. After classifying all pixels into the positive and negative groups, CAD computed a detection score based on the ratio of the number of positive pixels to all pixels in the segmented lung areas, which indicates the likelihood of the test case being positive for ILD. When applying to an independent testing dataset of 15 positive and 15 negative cases, the CAD scheme yielded the area under receiver operating characteristic curve (AUC = 0.884 ± 0.064) and 80.0% sensitivity at 85.7% specificity. The results demonstrated the feasibility of applying the CAD scheme to automatically detect early ILD using low-dose CT examinations.

Indexed as

Radiation DosageDiagnosis, Computer-AssistedEarly DiagnosisHumansImage Processing, Computer-AssistedLung Diseases, InterstitialLung NeoplasmsRetrospective StudiesTomography, X-Ray Computed

Identifiers

PMID21263171
PMCPMC3165025

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.