Evidence map›Paper›PMID 21263078›Full record

Trial reportArchives of internal medicine2011

Efficacy of brief behavioral treatment for chronic insomnia in older adults.

Daniel J Buysse, Anne Germain, Douglas E Moul, Peter L Franzen, Laurie K Brar, Mary E Fletcher, Amy Begley, Patricia R Houck, Sati Mazumdar, Charles F Reynolds and 1 more

Erratum issued 3 registry-linked trialsOpen access · greenAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Archives of internal medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 3 registered trials, which are not on this map. Cited by 243 papers, 13 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
243citing papers in PubMed, 13 pooled it
30.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00177203 nacompletednot on this map

Agewise Project 3: Brief Behavioral Treatment of Insomnia in Primary Care

TypeinterventionalSponsorUniversity of PittsburghRan2003 to 2009Enrolled140ConditionsInsomniaArmsBrief Behavioral Treatment of Insomnia or Information
NCT04783519 nacompletednot on this mapstarted 2021, after this paper: background citation

Research Evaluating Sleep & Trends for Universal Prevention

TypeinterventionalSponsorUniversity of WashingtonRan2021 to 2023Enrolled150ConditionsInsomnia, Alcohol Use, Unspecified, Marijuana UseArmsBrief Behavioral Therapy for Insomnia (BBTI), Brief Alcohol Screening and Intervention for College Students (BASICS)
NCT07779499 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Effectiveness of a Group-Based Brief Behavioral Therapy for Insomnia for Patients With Chronic Mental Illness

TypeinterventionalSponsorNational Taiwan University HospitalRan2026 to 2026Enrolled120ConditionsInsomniaArmsBrief Behavioral Treatment for Insomnia in chronic mental health
3 · Its place in the literature

Who cites it

243 citing papers in PubMed, 13 syntheses or guidelines pooled it, 540 citations in OpenAlex.

  1. Pooled it
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  3. Treatment of restless legs syndrome and periodic limb movement disorder: an American Academy of Sleep Medicine systematic review, meta-analysis, and GRADE assessment.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
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  5. Referral of adults with obstructive sleep apnea for surgical consultation: an American Academy of Sleep Medicine systematic review, meta-analysis, and GRADE assessment.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021
    Pooled it
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  8. Cognitive behavioural treatment for insomnia in primary care: a systematic review of sleep outcomes.The British journal of general practice : the journal of the Royal College of General Practitioners · 2019
    Pooled it
  9. Treatment of Adult Obstructive Sleep Apnea With Positive Airway Pressure: An American Academy of Sleep Medicine Systematic Review, Meta-Analysis, and GRADE Assessment.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2019
    Pooled it
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  12. Efficacy of cognitive behavioral therapy in children and adolescents with insomnia: a systematic review and meta-analysis.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2018
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183 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Daniel J BuysseSleep Medicine Institute, Department of Psychiatry, University of Pittsburgh School of Medicine, USA. buyssedj@upmc.edu
Anne Germain
Douglas E Moul
Peter L Franzen
Laurie K Brar
Mary E Fletcher
Amy Begley
Patricia R Houck
Sati Mazumdar
Charles F Reynolds
Timothy H Monk
University of Pittsburgh · US

Funding

UNIVERSITY OF PITTSBURGH CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTE: BPCAUL1RR024153 · NCRR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2006 to 2011
$73.9M
University of Pittsburgh Clinical and Translational Science InstituteUL1TR000005 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$50.8M
REDUCING STRESS /SLEEP DISTURBANCES IN CAREGIVERS OF ADP01AG020677 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BUYSSE, DANIEL J. · 2003 to 2015
$17.5M
RATIONAL PHARMACOTHERAPY OF PRIMARY INSOMNIAK24AG000972 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BUYSSE, DANIEL J. · 2000 to 2004
$505k
NCATS NIH HHS UL1 TR000005NCRR NIH HHS RR024153NCRR NIH HHS UL1 RR024153NIA NIH HHS AG000972NIA NIH HHS AG020677NIA NIH HHS K24 AG000972NIA NIH HHS P01 AG020677
6 · The paper itself

Abstract

backgroundChronic insomnia is a common health problem with substantial consequences in older adults. Cognitive behavioral treatments are efficacious but not widely available. The aim of this study was to test the efficacy of brief behavioral treatment for insomnia (BBTI) vs an information control (IC) condition.

methodsA total of 79 older adults (mean age, 71.7 years; 54 women [70%]) with chronic insomnia and common comorbidities were recruited from the community and 1 primary care clinic. Participants were randomly assigned to either BBTI, consisting of individualized behavioral instructions delivered in 2 intervention sessions and 2 telephone calls, or IC, consisting of printed educational material. Both interventions were delivered by a nurse clinician. The primary outcome was categorically defined treatment response at 4 weeks, based on sleep questionnaires and diaries. Secondary outcomes included self-report symptom and health measures, sleep diaries, actigraphy, and polysomnography.

resultsCategorically defined response (67% [n = 26] vs 25% [n = 10]; χ(2) = 13.8) (P < .001) and the proportion of participants without insomnia (55% [n = 21] vs 13% [n = 5]; χ(2) = 15.5) (P < .001) were significantly higher for BBTI than for IC. The number needed to treat was 2.4 for each outcome. No differential effects were found for subgroups according to hypnotic or antidepressant use, sleep apnea, or recruitment source. The BBTI produced significantly better outcomes in self-reported sleep and health (group × time interaction, F(5,73) = 5.99, P < .001), sleep diary (F(8,70) = 4.32, P < .001), and actigraphy (F(4,74) = 17.72, P < .001), but not polysomnography. Improvements were maintained at 6 months.

conclusionWe found that BBTI is a simple, efficacious, and durable intervention for chronic insomnia in older adults that has potential for dissemination across medical settings.

trial registrationclinicaltrials.gov Identifier: NCT00177203.

Indexed as

AgedAge FactorsBehavior TherapyFemaleFollow-Up StudiesHumansMaleMiddle AgedPatient Education as TopicPatient SatisfactionRisk AssessmentSeverity of Illness IndexSex FactorsSleep Initiation and Maintenance DisordersTeaching MaterialsTime Factors

Identifiers

PMID21263078
PMCPMC3101289
OpenAlexW2117075389

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.