ReviewMicrobial biotechnology2009
Chitosan and its antimicrobial potential--a critical literature survey.
Review in Microbial biotechnology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 209 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
209 citing papers in PubMed, 1 synthesis or guideline pooled it, 909 citations in OpenAlex.
- Chitosan Use in Dentistry: A Systematic Review of Recent Clinical Studies.Marine drugs · 2019Pooled it
- Effect of antiseptic gels in the microbiologic colonization of the suture threads after oral surgery.Scientific reports · 2020Trial
- Transforming Pediatric Dentistry with Chitosan Gel: Current Evidence and Emerging Trends-A Scoping Review.Materials (Basel, Switzerland) · 2026Review
- Molecular modeling characterization of cellulose and chitosan metal oxide hybrid interfaces.Scientific reports · 2026Article
- Critical Evaluation of Key Elements in Manufacturing Procedures and Testing Methodologies for Ocular Anti-Infective Thin Film Inserts.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Beyond Antibiotics: The Role of Antimicrobial Polymers in Modern Therapeutics.Pharmaceutics · 2026Review
- Recent advances in chitosan-based nanomaterials for enhanced antimicrobial activity.World journal of microbiology & biotechnology · 2026Review
- Review
- Sulfated Chitosan Induces Membrane Disruption, Aggregation, and Antibiofilm Activity inAntibiotics (Basel, Switzerland) · 2026Article
- Harnessing Microbial Consortia for Sustainable Agriculture: Abiotic and Biotic Stress Mitigation.Current microbiology · 2026Review
- Chitosan-Loaded Inorganic Oxide Nanocomposites (SiOFoods (Basel, Switzerland) · 2026Article
- Antibacterial effect of banana leaf extract-coated sutures against oral pathogens and MRSA: an in vitro study.Oral and maxillofacial surgery · 2026Article
- Chitosan in regenerative medicine: a translational perspective on biomaterial design.Frontiers in bioengineering and biotechnology · 2026Review
- Flexible and elastic chitosan-based hydrogel film dressings for second-degree partial-thickness burn wound healing.Journal of materials science. Materials in medicine · 2025Article
- Curcumin-Loaded Polysaccharide Nanoparticles Enhance Aqueous Dispersibility and In Vitro Cytotoxicity in Breast Cancer Cell Lines.Nanomaterials (Basel, Switzerland) · 2025Article
- Chitosan Derivatives Associated with Ceftazidime: Study of Controlled Release and Antibacterial Activity.ACS omega · 2025Article
- Inhibition ofMicroorganisms · 2025Article
- Quaternized chitosan derivatives inhibit growth and affect biofilm formation of Staphylococcus aureus.Scientific reports · 2025Article
- Rice bran protein-chitosan nanoparticle as a delivery system of ε-polylysine: preparation, characterization, antioxidant and antibacterial activity.Food chemistry: X · 2025Article
- Tunable physical properties and dye removal application of novel Chitosan Polyethylene glycol and polypyrrole/carbon black films.Scientific reports · 2025Article
149 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chitosan, an aminopolysaccharide biopolymer, has a unique chemical structure as a linear polycation with a high charge density, reactive hydroxyl and amino groups as well as extensive hydrogen bonding. It displays excellent biocompatibility, physical stability and processability. The term 'chitosan' describes a heterogeneous group of polymers combining a group of physicochemical and biological characteristics, which allow for a wide scope of applications that are both fascinating and as yet uncharted. The increased awareness of the potentials and industrial value of this biopolymer lead to its utilization in many applications of technical interest, and increasingly in the biomedical arena. Although not primarily used as an antimicrobial agent, its utility as an ingredient in both food and pharmaceutical formulations lately gained more interest, when a scientific understanding of at least some of the pharmacological activities of this versatile carbohydrate began to evolve. However, understanding the various factors that affect its antimicrobial activity has become a key issue for a better usage and a more efficient optimization of chitosan formulations. Moreover, the use of chitosan in antimicrobial systems should be based on sufficient knowledge of the complex mechanisms of its antimicrobial mode of action, which in turn would help to arrive at an appreciation of its entire antimicrobial potential.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.