ReviewMicrobial biotechnology2009
Microbial degradation of lignin: how a bulky recalcitrant polymer is efficiently recycled in nature and how we can take advantage of this.
Review in Microbial biotechnology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 127 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
127 citing papers in PubMed, 546 citations in OpenAlex.
- Characterization of successiveApplied and environmental microbiology · 2026Article
- Multimodal Analysis and Heterologous Expression Strategies Reveal the Crucial Role of the Lac2 Gene fromJournal of fungi (Basel, Switzerland) · 2026Article
- New Cross-Linked Polymeric Materials Modified with Antimicrobial Compounds in Relation to Their Biological Activities and Biodegradation by the Laccase-Producing FungusBiomolecules · 2026Article
- Plant-Based Scaffolds in Tissue Engineering: Structure-Function, Processing, and Clinical Outlook-A Review.Annals of biomedical engineering · 2026Review
- Evaluating the impact of boiling and roasting on the properties of cashew nutshells (Anacardium occidentale L.) for biomass valorization.Scientific reports · 2026Article
- Adaptive evolution of Agaricomycetes laccases follows wood lignin diversification in plants.Applied and environmental microbiology · 2026Article
- From waste to wealth: effects of nine agroforestry wastes on Stropharia's traits & yield.Open life sciences · 2026Article
- Microbial responses to ocean deoxygenation: Revisiting the impacts on organic carbon cycling.iScience · 2025Review
- Nanocellulose Extraction from Biomass Waste: Unlocking Sustainable Pathways for Biomedical Applications.Chemical record (New York, N.Y.) · 2025Review
- Mr-lac3 and Mr-lcc2 inJournal of fungi (Basel, Switzerland) · 2025Article
- Enzymatic Degradation of PFAS: Current Status and Ongoing Challenges.ChemSusChem · 2025Review
- Tools for genetic engineering and gene expression control inApplied and environmental microbiology · 2024Article
- Disproportionate Carbon Dioxide Efflux in Bacterial Metabolic Pathways for Different Organic Substrates Leads to Variable Contribution to Carbon-Use Efficiency.Environmental science & technology · 2024Article
- Structure-function characterization of two enzymes from novel subfamilies of manganese peroxidases secreted by the lignocellulose-degrading Agaricales fungi Agrocybe pediades and Cyathus striatus.Biotechnology for biofuels and bioproducts · 2024Article
- FromScience advances · 2024Article
- Spotlight on overlooked lignin monomers: Hydroxycinnamaldehydes.Plant physiology · 2024Article
- Article
- Relative contribution of photodegradation to litter breakdown in Australian grasslands.Ecology and evolution · 2023Article
- Article
- Origin, Selection, and Succession of Coastal Intertidal Zone-Derived Bacterial Communities Associated with the Degradation of Various Lignocellulose Substrates.Microbial ecology · 2023Article
67 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lignin is the second most abundant constituent of the cell wall of vascular plants, where it protects cellulose towards hydrolytic attack by saprophytic and pathogenic microbes. Its removal represents a key step for carbon recycling in land ecosystems, as well as a central issue for industrial utilization of plant biomass. The lignin polymer is highly recalcitrant towards chemical and biological degradation due to its molecular architecture, where different non-phenolic phenylpropanoid units form a complex three-dimensional network linked by a variety of ether and carbon-carbon bonds. Ligninolytic microbes have developed a unique strategy to handle lignin degradation based on unspecific one-electron oxidation of the benzenic rings in the different lignin substructures by extracellular haemperoxidases acting synergistically with peroxide-generating oxidases. These peroxidases poses two outstanding characteristics: (i) they have unusually high redox potential due to haem pocket architecture that enables oxidation of non-phenolic aromatic rings, and (ii) they are able to generate a protein oxidizer by electron transfer to the haem cofactor forming a catalytic tryptophanyl-free radical at the protein surface, where it can interact with the bulky lignin polymer. The structure-function information currently available is being used to build tailor-made peroxidases and other oxidoreductases as industrial biocatalysts.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.