Trial reportHernia : the journal of hernias and abdominal wall surgery2011
Prospective randomized evaluation of prophylactic antibiotic usage in patients undergoing tension free inguinal hernioplasty.
Trial report in Hernia : the journal of hernias and abdominal wall surgery, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 5 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- The role of prophylactic antibiotics in elective inguinal tension-free hernia repair: A systematic review and meta-analysis.International wound journal · 2023Pooled it
- Antibiotic prophylaxis for prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernia repair.The Cochrane database of systematic reviews · 2020Pooled it
- Network meta-analysis of antibiotic prophylaxis for prevention of surgical-site infection after groin hernia surgery.The British journal of surgery · 2017Pooled it
- Antibiotic prophylaxis for open mesh repair of groin hernia: systematic review and meta-analysis.Hernia : the journal of hernias and abdominal wall surgery · 2016Pooled it
- Antibiotic prophylaxis for hernia repair.The Cochrane database of systematic reviews · 2012Pooled it
- Patient Experience and Outcomes of the Locally Organized ApriDec Medical Outreach Group.World journal of surgery · 2020Article
- Antibiotics for Groin Hernia Repair According to Evidence-Based Guidelines: Time for Action in Ghana.The Journal of surgical research · 2019Article
- Commentary: Hernia, Mesh, and Topical Antibiotics, Especially Gentamycin: Seeking the Evidence for the Perfect Outcome….Frontiers in surgery · 2017Article
- The effectiveness of i.v. cefuroxime prophylaxis of surgical site infection after elective inguinal hernia repair with mesh: A retrospective observational study.European journal of clinical pharmacology · 2016Observational
- Antibiotic prophylaxis in open inguinal hernia repair: a literature review and summary of current knowledge.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2016Review
- Comparison between outcome of single dose of prophylactic antibiotic versus postoperative antibiotic in inguinal hernia surgery.Pakistan journal of medical sciencesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesAssessment of the usefulness of antibiotic prophylaxis in inguinal hernioplasty. MATERIALS AND
methodsThis prospective randomized double blind study was conducted on 98 patients. Group A (50 patients) received a single dose of intravenous amoxicillin and clavulanic acid, and Group P (48 patients) received an equal volume of normal saline placebo by intravenous bolus 30 min before the induction of anesthesia. Hernioplasty was performed with polypropylene mesh. Skin was closed using skin staples that were removed after complete wound healing. The surgical site infection was diagnosed according to APIC, CDC criteria ( http://www.apic.org ).
resultsThe mean operative time was 38.8 ± 10.8 min in group A versus 40.9 ± 11.1 min in group P (P = 0.34). The mean hospitalization time was 1.3 ± 0.463 days in group A versus 1.25 ± 0.438 days in group P (P = 0.58). Four patients (2%) in group A and 6 patients (2.88%) in group P had wound infections (P = 0.47). Group A had 3 superficial infections and 1 deep infection while group P had 5 superficial infections and 1 deep infection. Antibiotic treatment of the wound infection was successful in all patients. Wound culture showed Staphylococcus aureus infection in 1 patient each group, Streptococcus pyogenes in 1 group A patient and Pseudomonas aeruginosa in 1 group P patient. Cultures in other patients in both groups were reported to be sterile.
conclusionProphylactic antibiotic usage in patients undergoing tension free inguinal hernioplasty did not show any statistically significant beneficial effects in reduction of surgical site infection.
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