Evidence map›Paper›PMID 21258973›Full record

ReviewCurrent gastroenterology reports2011

New developments in pancreatic cancer.

Julia B Greer, Randall E Brand

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current gastroenterology reports, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Role of vitamin D receptor gene polymorphisms in pancreatic cancer: a case-control study in China.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2015
    Article
  9. Dietary food groups intake and cooking methods associations with pancreatic cancer: a case-control study.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2015
    Article
  10. Article
  11. Article
  12. Pancreatic cancer screening.Gastroenterology clinics of North America · 2012
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Julia B GreerDepartment of Medicine, Division of Gastroenterology, Hepatology, and Nutrition, University of Pittsburgh School of Medicine, Medical Arts Building, 3708 Fifth Avenue, Fourth Floor, Pittsburgh, PA 15213, USA. greerjb@upmc.edu
Randall E Brand

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic adenocarcinoma presents in an advanced stage and has a dismal prognosis. Extensive recent research efforts have provided us with greater insight into the etiology of pancreatic cancer and have also improved our means of prognostication. Molecular analysis demonstrated that specific pathways involved in pancreatic carcinogenesis are perhaps more valuable to study than single genetic aberrations. Previous risk factors, including family history, body mass index, and current cigarette smoking, were validated and novel risks, such as ABO blood group alleles, were identified. Similar to other illnesses, combinations of healthful habits, such as not smoking, adhering to a Mediterranean dietary pattern, and engaging in physical activity, may decrease pancreatic cancer risk. Finally, CA 19-9 levels, the presence of diabetes mellitus, and a six-gene signature provided critical information regarding survival that could help guide treatment of individuals diagnosed with pancreatic adenocarcinoma.

Indexed as

AdenocarcinomaAdiposityAlcohol DrinkingBlood Group AntigensBody Mass IndexCA-19-9 AntigenDietFanconi Anemia Complementation Group N ProteinFolic AcidHeredityHumansMutationNuclear ProteinsPancreatic NeoplasmsPrognosisRisk FactorsBlood Group AntigensCA-19-9 AntigenFanconi Anemia Complementation Group N ProteinFolic AcidNuclear ProteinsPALB2 protein, humanTumor Suppressor ProteinsVitamin D

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.