Evidence map›Paper›PMID 21258668›Full record

ReviewCanadian journal of gastroenterology = Journal canadien de gastroenterologie2011

Diagnosis and pharmacological management of small intestinal bacterial overgrowth in children with intestinal failure.

Bushra Aziz Malik, Yuan Y Xie, Eytan Wine, Hien Q Huynh

Abstract readReview
In one paragraph

Review in Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Pediatric Intestinal Failure Review.Children (Basel, Switzerland) · 2018
    Review
  8. Article
  9. Cystic fibrosis from the gastroenterologist's perspective.Nature reviews. Gastroenterology & hepatology · 2016
    Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bushra Aziz MalikDepartment of Medicine, University of Alberta, Edmonton, Alberta.
Yuan Y Xie
Eytan Wine
Hien Q Huynh

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present article provides a general overview of the possible diagnostic procedures available for the management of small intestinal bacterial overgrowth in pediatric patients with intestinal failure. The focus is to address current diagnostic tools and understand their associated advantages and disadvantages based on a literature search. Culture of small intestinal aspirates, noninvasive breath tests and an emerging interest in quantitative bacterial DNA fingerprinting are discussed. Proper management is critical for preventing the recurrence of small intestinal bacterial overgrowth and its related complications. Antibiotic prophylaxis is one approach to the treatment of bacterial overgrowth in intestinal failure patients. Although treatment trials can be challenging in such a vulnerable population, more investigative clinical studies examining early diagnosis, more effective control of recurrence and the prevention of associated complications must be conducted.

Indexed as

Breath TestsColony Count, MicrobialDNA FingerprintingHumansIntestinal DiseasesIntestine, SmallMalabsorption Syndromes

Identifiers

PMID21258668
PMCPMC3027334

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.