ArticleBiomedical optics express2010
A Bayesian method for single molecule, fluorescence burst analysis.
Article in Biomedical optics express, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed.
- Building Fluorescence Lifetime Maps Photon-by-Photon by Leveraging Spatial Correlations.ACS photonics · 2023Article
- High Resolution Fluorescence Lifetime Maps from Minimal Photon Counts.ACS photonics · 2022Article
- Complex wavelet filter improves FLIM phasors for photon starved imaging experiments.Biomedical optics express · 2021Article
- Nonparametric empirical Bayesian framework for fluorescence-lifetime imaging microscopy.Biomedical optics express · 2019Article
- Article
- Time-domain microfluidic fluorescence lifetime flow cytometry for high-throughput Förster resonance energy transfer screening.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2015Article
- Single-molecule enzymatic conformational dynamics: spilling out the product molecules.The journal of physical chemistry. B · 2014Article
- On-the-fly decoding luminescence lifetimes in the microsecond region for lanthanide-encoded suspension arrays.Nature communications · 2014Article
- Analyzing conformational dynamics of single P-glycoprotein transporters by Förster resonance energy transfer using hidden Markov models.Methods (San Diego, Calif.) · 2014Article
- Total variation versus wavelet-based methods for image denoising in fluorescence lifetime imaging microscopy.Journal of biophotonics · 2012Article
- Time-domain fluorescence lifetime imaging techniques suitable for solid-state imaging sensor arrays.Sensors (Basel, Switzerland) · 2012Article
- Article
- FLIM-FRET for Cancer Applications.Current molecular imagingArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is currently great interest in determining physical parameters, e.g. fluorescence lifetime, of individual molecules that inform on environmental conditions, whilst avoiding the artefacts of ensemble averaging. Protein interactions, molecular dynamics and sub-species can all be studied. In a burst integrated fluorescence lifetime (BIFL) experiment, identification of fluorescent bursts from single molecules above background detection is a problem. This paper presents a Bayesian method for burst identification based on model selection and demonstrates the detection of bursts consisting of 10% signal amplitude. The method also estimates the fluorescence lifetime (and its error) from the burst data.
Identifiers
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Registered trials
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