ArticlePlant physiology2011
The Arabidopsis mutant jason produces unreduced first division restitution male gametes through a parallel/fused spindle mechanism in meiosis II.
Article in Plant physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers.
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77 citing papers in PubMed.
- Newly unveiled meiosis elucidates the unreduced gamete frequency and its impact on the evolution of the Lemna minor complex.Journal of experimental botany · 2026Article
- Understanding and harnessing unreduced gametes for crop improvement.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Review
- Mei4 deficiency induces sexual dimorphism in early meiosis and promotes production of unreduced eggs in zebrafish.Zoological research · 2026Article
- A simple and high-throughput single pollen genotyping pipeline to study meiosis in apple (Malus x domestica).Plant methods · 2026Article
- Actin filaments drive spindle positioning in Arabidopsis meiosis II.The New phytologist · 2025Article
- Meiotic cytokinesis defects in cultured Arabidopsis flowers induce diploid microspores.Plant reproduction · 2025Article
- ClPS1 gene-mediated manipulation of 2n pollen formation enables the creation of triploid seedless watermelon.Molecular horticulture · 2025Article
- Duckweed genomes and epigenomes underlie triploid hybridization and clonal reproduction.Current biology : CB · 2025Article
- Rapid formation of stable autotetraploid rice from genome-doubled F1 hybrids of japonica-indica subspecies.Nature plants · 2025Article
- Meiosis in bulbous flower speciesFrontiers in plant science · 2025Article
- Targeted suppression of siRNA biogenesis in Arabidopsis pollen promotes triploid seed viability.Nature communications · 2024Article
- Identification of two mutant JASON-RELATED genes associated with unreduced pollen production in potato.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Formation of Different Polyploids Through Disrupting Meiotic Crossover Frequencies Based on cntd1 Knockout in Zebrafish.Molecular biology and evolution · 2024Article
- Crossover shortage in potato is caused by StMSH4 mutant alleles and leads to either highly uniform unreduced pollen or sterility.Genetics · 2024Article
- Engineering apomixis in crops.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Review
- Haploid male fertility is restored by parallel spindle genes in Arabidopsis thaliana.Nature plants · 2023Article
- A genetic mechanism to restore haploid male fertility in Arabidopsis - an alternative to chemical methods.Nature plants · 2023Article
- The scaffold nucleoporins SAR1 and SAR3 are essential for proper meiotic progression inFrontiers in cell and developmental biology · 2023Article
- Creating novel ornamentalsFrontiers in plant science · 2023Review
- Heat shock-induced failure of meiosis I to meiosis II transition leads to 2n pollen formation in a woody plant.Plant physiology · 2022Article
17 more citing papers are in PubMed but not listed here.
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2 authors.
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Abstract
In plants, whole-genome doubling (polyploidization) is a widely occurring process largely contributing to plant evolution and diversification. The generation and fusion of diploid gametes is now considered the major route of plant polyploidization. The parallel arrangement or fusion of meiosis II MII spindles (ps) is one of the most frequently reported mechanisms generating triploid offspring. Through a forward genetics screen of an Arabidopsis (Arabidopsis thaliana) ethyl methanesulfonate population, we identified Arabidopsis thaliana Parallel Spindles1 (AtPS1), which was recently reported as a major gene implicated in the control of the ps meiotic defect. In addition, we describe the isolation and characterization of a novel allele of JASON, involved in male gametophytic ploidy regulation in plants. Similar to atps1 mutants, jason produces more than 25% 2n pollen grains and spontaneously forms triploid offspring. By combining both cytological and genetic approaches, we demonstrate that loss of JASON causes the formation of parallel arranged and fused spindles in male MII, resulting in the production of unreduced first division restitution 2n spores. Although JASON encodes a protein of unknown function, we additionally show that the meiotic ps defect in jason is caused by a reduction in AtPS1 transcript levels, indicating that JASON positively regulates AtPS1 expression, allowing the proper organization and orientation of metaphase II spindle plates in MII.
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