ReviewActa biochimica et biophysica Sinica2011
Protein microarrays for systems biology.
Review in Acta biochimica et biophysica Sinica, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 59 citations in OpenAlex.
- Current applications of antibody microarrays.Clinical proteomics · 2018Review
- An ABA-increased interaction of the PYL6 ABA receptor with MYC2 Transcription Factor: A putative link of ABA and JA signaling.Scientific reports · 2016Article
- PMD: A Resource for Archiving and Analyzing Protein Microarray data.Scientific reports · 2016Article
- Development of repeatable arrays of proteins using immobilized DNA microplate (RAPID-M) technology.BMC research notes · 2015Article
- The female gametophyte: an emerging model for cell type-specific systems biology in plant development.Frontiers in plant science · 2015Review
- Bcl2-associated athanogene 3 interactome analysis reveals a new role in modulating proteasome activity.Molecular & cellular proteomics : MCP · 2013Article
- Interactome mapping: using protein microarray technology to reconstruct diverse protein networks.Genomics, proteomics & bioinformatics · 2013Review
- Recent advances in diagnosis, prevention, and treatment of human respiratory syncytial virus.Advances in virology · 2013Review
- Plasmodium falciparum malaria: proteomic studies.Revista Brasileira de terapia intensiva · 2012Article
- Acupuncture activates signal transduction pathways related to brain-tissue restoration after ischemic injury.Neural regeneration research · 2012Article
- Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach.Oncology reports · 2012Article
- Global identification of prokaryotic glycoproteins based on an Escherichia coli proteome microarray.PloS one · 2012Article
- Identification of lactoferricin B intracellular targets using an Escherichia coli proteome chip.PloS one · 2011Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Systems biology holds the key for understanding biological systems on a system level. It eventually holds the key for the treatment and cure of complex diseases such as cancer, diabetes, obesity, mental disorders, and many others. The '-omics' technologies, such as genomics, transcriptomics, proteomics, and metabonomics, are among the major driving forces of systems biology. Featured as high-throughput, miniaturized, and capable of parallel analysis, protein microarrays have already become an important technology platform for systems biology. In this review, we will focus on the system level or global analysis of biological systems using protein microarrays. Four major types of protein microarrays will be discussed: proteome microarrays, antibody microarrays, reverse-phase protein arrays, and lectin microarrays. We will also discuss the challenges and future directions of protein microarray technologies and their applications for systems biology. We strongly believe that protein microarrays will soon become an indispensable and invaluable tool for systems biology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.