ArticleAmerican journal of infection control2011
Inactivation of surrogate coronaviruses on hard surfaces by health care germicides.
Article in American journal of infection control, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 4 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
51 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Disinfection methods against SARS-CoV-2: a systematic review.The Journal of hospital infection · 2022Pooled it
- A systematic review of emerging human coronavirus (SARS-CoV-2) outbreak: focus on disinfection methods, environmental survival, and control and prevention strategies.Environmental science and pollution research international · 2021Pooled it
- Alcohol-based hand sanitisers as first line of defence against SARS-CoV-2: a review of biology, chemistry and formulations.Epidemiology and infection · 2020Guideline
- Hand Sanitizers: A Review on Formulation Aspects, Adverse Effects, and Regulations.International journal of environmental research and public health · 2020Pooled it
- In vitro virucidal activity of chemical compounds against porcine transmissible gastroenteritis virus and porcine respiratory coronavirus.BMC veterinary research · 2025Article
- Changes in biosafety practices of Brazilian orthodontists after the COVID-19 pandemic: a cross-sectional study.Brazilian oral research · 2025Article
- Efficacy of Peracetic Acid and Sodium Hypochlorite against SARS-CoV-2 on Contaminated Surfaces.Applied and environmental microbiology · 2023Article
- Viability of SARS-CoV-2 on lettuce, chicken, and salmon and its inactivation by peracetic acid, ethanol, and chlorine dioxide.Food microbiology · 2023Article
- Inactivation Performance of Pseudorabies Virus as African Swine Fever Virus Surrogate by Four Commercialized Disinfectants.Vaccines · 2023Article
- Carbohydrate vitrification in aerosolized saliva is associated with the humidity-dependent infectious potential of airborne coronavirus.PNAS nexus · 2023Article
- Inactivation methods for human coronavirus 229E on various food-contact surfaces and foods.Food control · 2022Article
- Virucidal Efficacy of Laundering.Pathogens (Basel, Switzerland) · 2022Review
- Residual antimicrobial coating efficacy against SARS-CoV-2.Journal of applied microbiology · 2022Article
- Investigation of biocidal efficacy of commercial disinfectants used in public, private and workplaces during the pandemic event of SARS-CoV-2.Scientific reports · 2022Article
- Heat inactivation of clinical COVID-19 samples on an industrial scale for low risk and efficient high-throughput qRT-PCR diagnostic testing.Scientific reports · 2022Article
- [Health Technology Assessment of the Probiotic Cleaning Hygiene System (PCHS)].Journal of preventive medicine and hygiene · 2022Article
- New Countermeasures Against Infections with/after COVID-19: Is Chlorine Dioxide a Useful and Safe Disinfectant?Juntendo Iji zasshi = Juntendo medical journal · 2022Article
- Investigation on Potential ESKAPE Surrogates for 222 and 254 nm Irradiation Experiments.Frontiers in microbiology · 2022Article
- Effect of Sanitizer on obliteration of SARS -CoV2/COVID 19: A mini review.Materials today. Proceedings · 2022Article
- Inactivation of Replication-Competent Vesicular Stomatitis Virus as SARS-CoV-2 Surrogate on Common Surfaces by Disinfectants.International journal of environmental research and public health · 2021Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn the 2003 severe acute respiratory syndrome outbreak, finding viral nucleic acids on hospital surfaces suggested surfaces could play a role in spread in health care environments. Surface disinfection may interrupt transmission, but few data exist on the effectiveness of health care germicides against coronaviruses on surfaces.
methodsThe efficacy of health care germicides against 2 surrogate coronaviruses, mouse hepatitis virus (MHV) and transmissible gastroenteritis virus (TGEV), was tested using the quantitative carrier method on stainless steel surfaces. Germicides were o-phenylphenol/p-tertiary amylphenol) (a phenolic), 70% ethanol, 1:100 sodium hypochlorite, ortho-phthalaldehyde (OPA), instant hand sanitizer (62% ethanol), and hand sanitizing spray (71% ethanol).
resultsAfter 1-minute contact time, for TGEV, there was a log(10) reduction factor of 3.2 for 70% ethanol, 2.0 for phenolic, 2.3 for OPA, 0.35 for 1:100 hypochlorite, 4.0 for 62% ethanol, and 3.5 for 71% ethanol. For MHV, log(10) reduction factors were 3.9 for 70% ethanol, 1.3 for phenolic, 1.7 for OPA, 0.62 for 1:100 hypochlorite, 2.7 for 62% ethanol, and 2.0 for 71% ethanol.
conclusionOnly ethanol reduced infectivity of the 2 coronaviruses by >3-log(10) after 1 minute. Germicides must be chosen carefully to ensure they are effective against viruses such as severe acute respiratory syndrome coronavirus.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.