ReviewJournal of experimental & clinical cancer research : CR2011
The immunoregulatory mechanisms of carcinoma for its survival and development.
Review in Journal of experimental & clinical cancer research : CR, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 60 citations in OpenAlex.
- Live or Heat-KilledInternational journal of molecular sciences · 2022Article
- Review
- Prognostic value of Dickkopf-1 and ß-catenin expression according to the antitumor immunity of CD8-positive tumor-infiltrating lymphocytes in biliary tract cancer.Scientific reports · 2022Article
- Advances and challenges of immunocheckpoint inhibitors in the treatment of primary liver cancer.Frontiers in genetics · 2022Review
- Formation of pre-metastatic bone niche in prostate cancer and regulation of traditional chinese medicine.Frontiers in pharmacology · 2022Review
- Pulmonary Inflammation and KRAS Mutation in Lung Cancer.Advances in experimental medicine and biology · 2021Article
- Hematological reactions in the inhabitants of the Arctic on a polar night and a polar day.Immunity, inflammation and disease · 2020Article
- Clinicopathologic significance of human leukocyte antigen class I expression in patients with stage II and III gastric cancer.Cancer immunology, immunotherapy : CII · 2019Article
- Prevention of Prostate Tumor Development by Stimulation of Antitumor Immunity Using a Standardized Herbal Extract (Deep Immune®) in TRAMP Mice.Evidence-based complementary and alternative medicine : eCAM · 2018Article
- Spontaneous regression of transverse colon cancer: a case report.Surgical case reports · 2017Article
- Major histocompatibility complex class I expression impacts on patient survival and type and density of immune cells in biliary tract cancer.British journal of cancer · 2015Article
- Vitamin D3 enhances the tumouricidal effects of 5-Fluorouracil through multipathway mechanisms in azoxymethane rat model of colon cancer.Journal of experimental & clinical cancer research : CR · 2015Article
- Embryonic stem cell-derived haematopoietic progenitor cells down-regulate the CD3 ξ chain on T cells, abrogating alloreactive T cells.Immunology · 2014Article
- Mannan-modified adenovirus encoding VEGFR-2 as a vaccine to induce anti-tumor immunity.Journal of cancer research and clinical oncology · 2014Article
- Prognostic impact of tumour-infiltrating immune cells on biliary tract cancer.British journal of cancer · 2013Article
- Silica-induced chronic inflammation promotes lung carcinogenesis in the context of an immunosuppressive microenvironment.Neoplasia (New York, N.Y.) · 2013Article
- A sensitivity scale for targeting T cells with chimeric antigen receptors (CARs) and bispecific T-cell Engagers (BiTEs).Oncoimmunology · 2012Article
- Galectin labeling of cells from paraffinized tissues may serve as a diagnostic tool in the detection and classification of thyroid carcinomas.Endocrine pathology · 2012Article
- The immunosuppressive factors IL-10, TGF-β, and VEGF do not affect the antigen-presenting function of CD40-activated B cells.Journal of experimental & clinical cancer research : CR · 2012Article
- Global gene expression changes in human urothelial cells exposed to low-level monomethylarsonous acid.Toxicology · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The immune system in patients detects and eliminates tumor cells, but tumors still progress persistently. The mechanisms by which tumor cells survive under the pressure of immune surveillance are not fully understood. This review is to present the evidence from clinical studies, showing a significant correlation of clinicopathological features of carcinoma with: (1) the loss of classical human leukocyte antigen class I, (2) the up-regulation of non-classical human leukocyte antigen class I, pro-apoptotic Fas ligand and receptor-binding cancer antigen expressed on SiSo cells I, and (3) the formation of immunosuppressive microenvironment by up-regulation of transforming growth factor-beta, Galectin-1, inhibitory ligand B7s, indoleamine 2,3-dioxygenase and arginase, as well as by recruitment of tumor-induced myeloid-derived suppressor cells and regulatory T cells. All of these factors may together protect carcinoma cells from the immune-cytotoxicity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.