ArticleJournal of thrombosis and haemostasis : JTH2011
Traffic exposure and incident venous thromboembolism in the Atherosclerosis Risk in Communities (ARIC) Study.
Article in Journal of thrombosis and haemostasis : JTH, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Air pollution and venous thrombosis: a meta-analysis.Scientific reports · 2016Pooled it
- Air, Noise, and Light Pollution and Thromboembolic Cardiovascular Complications: A TH Scientific Statement.Thrombosis and haemostasis · 2026Article
- Long-term exposure to air pollution and the risks of venous thromboembolism: a nationwide population-based retrospective cohort study.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Article
- Association of air pollution and atmospheric conditions on pulmonary embolism incidence and severity.Research and practice in thrombosis and haemostasis · 2026Article
- Article
- Long-term exposures to ambient particulate matter and ozone pollution with lower extremity deep vein thrombosis after surgical operations: a retrospective case-control study in Beijing, China.BMC public health · 2023Article
- Long-term air pollution exposure and markers of cardiometabolic health in the National Longitudinal Study of Adolescent to Adult Health (Add Health).Environment international · 2023Article
- Cigarette smoking and air pollution exposure and their effects on cardiovascular diseases.Frontiers in public health · 2023Review
- Correlation of Air Pollution and Prevalence of Acute Pulmonary Embolism in Northern Thailand.International journal of environmental research and public health · 2022Article
- Long-term exposure to air pollution and risk of venous thromboembolism in a large administrative cohort.Environmental health : a global access science source · 2022Article
- Novel evidence for a greater burden of ambient air pollution on cardiovascular disease.Haematologica · 2019Review
- Environmental and Genetic Risk Factors Associated with Venous Thromboembolism.Seminars in thrombosis and hemostasis · 2016Review
- Prospective Study of Ambient Particulate Matter Exposure and Risk of Pulmonary Embolism in the Nurses' Health Study Cohort.Environmental health perspectives · 2015Article
- Effects on health of air pollution: a narrative review.Internal and emergency medicine · 2015Review
- Expert position paper on air pollution and cardiovascular disease.European heart journal · 2015Article
- The cardiopulmonary effects of ambient air pollution and mechanistic pathways: a comparative hierarchical pathway analysis.PloS one · 2014Article
- Article
Corrections and comments
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Authors and funding
8 authors at 7 institutions in 2 countries.
Funding
Abstract
backgroundTwo recent case-control studies in Italy reported that long-term exposure to particulate air pollution or living near major traffic roads was associated with an increased risk of deep vein thrombosis (DVT). No prospective evidence exists on the possible association between long-term traffic-related air pollution and incident venous thromboembolism (VTE).
objectivesTo examine the association between long-term traffic exposure and incident VTE in a population-based prospective cohort study.
methodsWe studied 13,143 middle-aged men and women in the Atherosclerosis Risk in Communities Study without a history of DVT or pulmonary embolism at baseline examination (1987-1989). The Geographical Information System-mapped traffic density and distance to major roads in the four study communities served as measures of traffic exposure. We examined the association between traffic exposure and incident VTE with proportional hazards regression models.
resultsA total of 405 subjects developed VTE in 2005. Traffic density was not significantly associated with VTE. Relative to those in the lowest quartile of traffic density, the adjusted hazard ratios across increasing quartiles were 1.18 (95% confidence interval [CI] 0.88-1.57), 0.99 (95% CI 0.74-1.34) and 1.14 (95% CI 0.86-1.51) (P-value for trend across quartiles = 0.64). For residents living within 150 m of major roads, as compared with subjects living further away, the adjusted hazard ratio was 1.16 (95% CI 0.95-1.42, P = 0.14).
conclusionsThis first prospective study in the general population does not support an association between air pollution exposure or traffic proximity and risk of DVT. More data may be needed to clarify whether traffic or air pollution influences the risk of VTE.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.