Evidence map›Paper›PMID 21253854›Full record

ReviewNeurochemical research2011

Regulation of cortical neuron migration by the Reelin signaling pathway.

Takao Honda, Kazuma Kobayashi, Katsuhiko Mikoshiba, Kazunori Nakajima

Abstract readReview
PubMed Publisher
In one paragraph

Review in Neurochemical research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. HeterozygouseNeuro · 2023
    Article
  5. Article
  6. Diagnostic Approach to Cerebellar Hypoplasia.Cerebellum (London, England) · 2021
    Review
  7. Integrated genomic and transcriptomic analysis suggestsAnnals of translational medicine · 2021
    Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Structural and Synaptic Organization of the AdultFrontiers in neuroanatomy · 2018
    Article
  16. Review
  17. Reelin Deficiency Delays Mammary Tumor Growth and Metastatic Progression.Journal of mammary gland biology and neoplasia · 2017
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Takao HondaDepartment of Anatomy, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.
Kazuma Kobayashi
Katsuhiko Mikoshiba
Kazunori Nakajima

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reeler is a mutant mouse with defects in layered structures of the central nervous system, such as the cerebral cortex, hippocampus, and cerebellum, and has been extensively examined for more than half a century. The full-length cDNA for the responsible gene for reeler, reelin, was serendipitously identified, revealing that Reelin encodes a large secreted protein. So far, two Reelin receptors, apolipoprotein E receptor 2 and very low-density lipoprotein receptor, and the cytoplasmic adaptor protein Disabled homolog 1 (Dab1) have been shown to be essential for Reelin signaling. Although a number of downstream cascades of Dab1 have also been reported using various experimental systems, the physiological functions of Reelin in vivo remain controversial. Here, we review recent advances in the understanding of the Reelin-Dab1 signaling pathway in the developing cerebral cortex.

Indexed as

AnimalsCell Adhesion Molecules, NeuronalCell MovementCerebral CortexExtracellular Matrix ProteinsInterneuronsLDL-Receptor Related ProteinsMiceMice, Neurologic MutantsNerve Tissue ProteinsReceptors, LDLReelin ProteinSerine EndopeptidasesSignal TransductionCell Adhesion Molecules, NeuronalDab1 protein, mouseExtracellular Matrix ProteinsLDL-Receptor Related Proteinslow density lipoprotein receptor-related protein 8Nerve Tissue ProteinsReceptors, LDLReelin ProteinReln protein, mouseSerine EndopeptidasesVLDL receptor

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.