SynthesisWorld journal of gastroenterology2011
Effect of preoperative biliary drainage on malignant obstructive jaundice: a meta-analysis.
Synthesis in World journal of gastroenterology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 4 syntheses or guidelines pooled it, 84 citations in OpenAlex.
- Guidelines for Perioperative Care for Pancreatoduodenectomy: Enhanced Recovery After Surgery (ERAS) Recommendations 2019.World journal of surgery · 2020Pooled it
- Effect of Preoperative Biliary Drainage on Complications Following Pancreatoduodenectomy: A Meta-Analysis.Medicine · 2015Pooled it
- A meta-analysis of the effect of preoperative biliary stenting on patients with obstructive jaundice.Medicine · 2014Pooled it
- Guidelines for perioperative care for pancreaticoduodenectomy: Enhanced Recovery After Surgery (ERAS®) Society recommendations.World journal of surgery · 2013Guideline
- Preoperative biliary drainage using a fully covered self-expandable metallic stent for pancreatic head cancer: A prospective feasibility study.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology AssociationTrial
- Significance of Self-Expandable Metallic Stent for Postoperative Intra-Abdominal Infection After Pancreatoduodenectomy in Patients With a Hard Pancreas.Annals of gastroenterological surgery · 2026Article
- Oncologic effect of preoperative endoscopic sphincterotomy in patients undergoing pancreaticoduodenectomy for ampulla of vater cancer.Langenbeck's archives of surgery · 2025Article
- Diagnosis and Treatment of Perihilar Cholangiocarcinoma: A National Survey from the Korean Pancreatobiliary Association.Gut and liver · 2024Article
- A review of the current ERAS guidelines for liver resection, liver transplantation and pancreatoduodenectomy.Annals of medicine and surgery (2012) · 2022Review
- Pre-operative stenting and complications following pancreatoduodenectomy for pancreatic cancer: an analysis of the ACS-NSQIP registry.Surgical endoscopy · 2021Article
- A preliminary single-center investigation of percutaneous biliary stenting in malignant hilar biliary obstruction: what impacts the clinical success and the long-term outcomes?Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Article
- Advances in the management of cholangiocarcinoma.World journal of hepatology · 2021Review
- The pivotal predictor of severe postoperative complications of pancreatoduodenectomy: complex links of bacterial contamination from preoperative biliary drainage.Surgery today · 2020Article
- Current Endoscopic Management of Malignant Biliary Stricture.Medicina (Kaunas, Lithuania) · 2020Review
- Yinchenhao decoction attenuates obstructive jaundice-induced liver injury and hepatocyte apoptosis by suppressing protein kinase RNA-like endoplasmic reticulum kinase-induced pathway.World journal of gastroenterology · 2019Article
- Evaluation of the clinical and economic impact of delays to surgery in patients with periampullary cancer.BJS open · 2019Article
- Influence of Preoperative Endoscopic Retrograde Cholangiopancreatography (ERCP) on Bacterial Colonization of Biliary Tract in Patients Surgically Treated for Obstructive Jaundice.Materia socio-medica · 2019Article
- Effectiveness and risk of biliary drainage prior to pancreatoduodenectomy: review of current status.Surgery today · 2018Review
- The Effect of Preoperative Biliary and Pancreatic Drainage on Postoperative Pancreatic Fistula: A Retrospective Cohort Study.Surgery journal (New York, N.Y.) · 2018Article
- Bare-metal stents across the Vater's ampulla is a safe method for patients with lower bile duct obstruction.Medicine · 2017Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo evaluate the effect of preoperative biliary drainage (PBD) on obstructive jaundice resulting from malignant tumors.
methodsAccording to the requirements of Cochrane systematic review, studies in the English language were retrieved from MEDLINE and Embase databases from 1995 to 2009 with the key word "preoperative biliary drainage". Two reviewers independently screened the eligible studies, evaluated their academic level and extracted the data from the eligible studies confirmed by cross-checking. Data about patients with and without PBD after resection of malignant tumors were processed for meta-analysis using the Stata 9.2 software, including postoperative mortality, incidence of postoperative pancreatic and bile leakage, abdominal abscess, delayed gastric emptying and incision infection.
resultsFourteen retrospective cohort studies involving 1826 patients with malignant obstructive jaundice accorded with our inclusion criteria, and were included in meta-analysis. Their baseline characteristics were comparable in all the studies. No significant difference was found in combined risk ratio (RR) of postoperative mortality and incidence of pancreatic and bile leakage, abdominal abscess, delayed gastric emptying between patients with and without PBD. However, the combined RR for the incidence of postoperative incision infection was improved better in patients with PBD than in those without PBD (P < 0.05).
conclusionPBD cannot significantly reduce the postoperative mortality and complications of malignant obstructive jaundice, and therefore should not be used as a preoperative routine procedure for malignant obstructive jaundice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.