Evidence map›Paper›PMID 21253345›Full record

ArticleIndian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine2010

Acute kidney injury after trauma: Prevalence, clinical characteristics and RIFLE classification.

Krasnalhia Lívia S de Abreu, Geraldo B Silva Júnior, Adller G C Barreto, Fernanda M Melo, Bárbara B Oliveira, Rosa M S Mota, Natália A Rocha, Sônia L Silva, Sônia M H A Araújo, Elizabeth F Daher

Registry-linked trialAbstract read
In one paragraph

Article in Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06177886 (Incidence and Predictive Risk Factors of Acute Kidney Injury in Pediatric Polytrauma Patients Admitted to Assiut University Trauma Unit), which is not on this map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06177886 unknown statusnot on this mapstarted 2024, after this paper: background citation

Incidence and Predictive Risk Factors of Acute Kidney Injury in Pediatric Polytrauma Patients Admitted to Assiut University Trauma Unit: a Cross-sectional Study

TypeobservationalSponsorAssiut UniversityRan2024 to 2025Enrolled100ConditionsAcute Kidney Injury
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Role of Urinary Biomarkers TIMP-2 and IGFBP7 in Predicting Acute Kidney Injury in Critically Ill Trauma Patients: A Prospective Observational Study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2025
    Article
  5. Article
  6. Epidemiology of postinjury multiple organ failure: a prospective multicenter observational study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024
    Observational
  7. NADCell communication and signaling : CCS · 2024
    Review
  8. Article
  9. Occurrence of cardiovascular events in 168 cats with acute urinary tract obstruction.The Canadian veterinary journal = La revue veterinaire canadienne · 2024
    Article
  10. Article
  11. Experimental Cardiorenal Syndrome Type 3: What Is Known so Far?Journal of clinical medicine research · 2022
    Review
  12. Kidney-Related Outcome in Cardiorenal Syndrome Type 3.International journal of nephrology · 2022
    Article
  13. Article
  14. Prevalence and risk factors of acute kidney injury in polytrauma patients at Muhimbili Orthopedic Institute, Tanzania.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2021
    Article
  15. Observational
  16. The incidence and outcomes of patients with acute kidney injury in a multidisciplinary intensive care unit in Durban, South Africa.The Southern African journal of critical care : the official journal of the Critical Care Society · 2020
    Article
  17. Article
  18. Host responses to concurrent combined injuries in non-human primates.Journal of inflammation (London, England) · 2017
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Krasnalhia Lívia S de AbreuDivision of Nephrology, Department of Internal Medicine, School of Medicine, Walter Cantídio University Hospital, Ceará, Brazil.
Geraldo B Silva Júnior
Adller G C Barreto
Fernanda M Melo
Bárbara B Oliveira
Rosa M S Mota
Natália A Rocha
Sônia L Silva
Sônia M H A Araújo
Elizabeth F Daher

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute kidney injury (AKI) is an uncommon but serious complication after trauma. The objective of this study was to evaluate the prevalence, clinical characteristics and outcome of AKI after trauma. PATIENTS AND

methodsThis was a retrospective study performed from January 2006 to January 2008 in an emergency specialized hospital in Fortaleza city, northeast of Brazil. All patients with AKI admitted in the study period were included. Prevalence of AKI, clinical characteristics and outcome were investigated.

resultsOf the 129 patients admitted to the intensive care unit (ICU), 52 had AKI. The mean age was 30.1 ± 19.2 years, and 79.8% were males. The main causes of AKI were sepsis in 27 cases (52%) and hypotension in 18 (34%). Oliguria was observed in 33 cases (63%). Dialysis was required for 19 patients (36.5%). Independent risk factors associated with AKI were abdominal trauma [odds ratio (OR) = 3.66, P = 0.027] and use of furosemide (OR = 4.10, P = 0.026). Patients were classified according to RIFLE criteria as Risk in 12 cases (23%), Injury in 13 (25%), Failure in 24 (46%), Loss in 1 (2%) and End-stage in 2 (4%). Overall in-hospital mortality was 95.3%. The main cause of death was sepsis (24%). Mortality was 100% among patients with AKI.

conclusionsAKI is a fatal complication after trauma, which presented with a high mortality in the studied population. A better comprehension of factors associated with death in trauma-associated AKI is important, and more effective measures of prevention and treatment of AKI in this population are urgently needed.

Indexed as

Acute kidney injurymortalityoutcomerisk factorstrauma

Identifiers

PMID21253345
PMCPMC3021827

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.