Evidence map›Paper›PMID 21252983›Full record

ReviewLeukemia2011

Immunophenotyping of acute leukemia and lymphoproliferative disorders: a consensus proposal of the European LeukemiaNet Work Package 10.

M C Béné, T Nebe, P Bettelheim, B Buldini, H Bumbea, W Kern, F Lacombe, P Lemez, I Marinov, E Matutes and 10 more

Abstract readReviewConsensus Statement
PubMed Publisher
In one paragraph

Review in Leukemia, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 3 pooled it
9.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 3 syntheses or guidelines pooled it, 213 citations in OpenAlex.

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  13. Acute lymphoblastic leukaemia.Nature reviews. Disease primers · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 17 institutions in 10 countries.

M C BénéImmunology Laboratory, CHU de Brabois & Nancy Université, Vandoeuvre les Nancy, France. bene@medecine.uhp-nancy.fr
T Nebe
P Bettelheim
B Buldini
H Bumbea
W Kern
F Lacombe
P Lemez
I Marinov
E Matutes
M Maynadié
U Oelschlagel
A Orfao
R Schabath
M Solenthaler
G Tschurtschenthaler
A M Vladareanu
G Zini
G C Faure
A Porwit
Carol Davila University of Medicine and Pharmacy · ROCentre Hospitalier Régional et Universitaire de Nancy · FRCentro de Investigación del Cáncer · ESCHU Dijon Bourgogne · FREndokrinologikum · DEHelios Hospital Berlin-Buch · DEHôpital Cardiologique du Haut-Lévêque · FRHospital Jihlava · CZInstitute of Cancer Research · GBInstitute of Haematology and Blood Transfusion · CZKarolinska University Hospital · SEKrankenhaus der Elisabethinen · ATMunich Leukemia Laboratory (Germany) · DEOrdensklinikum Linz Barmherzige Schwestern · ATUniversità Cattolica del Sacro Cuore · ITUniversity of Bern · CHUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The European LeukemiaNet (ELN), workpackage 10 (WP10) was designed to deal with diagnosis matters using morphology and immunophenotyping. This group aimed at establishing a consensus on the required reagents for proper immunophenotyping of acute leukemia and lymphoproliferative disorders. Animated discussions within WP10, together with the application of the Delphi method of proposals circulation, quickly led to post-consensual immunophenotyping panels for disorders on the ELN website. In this report, we established a comprehensive description of these panels, both mandatory and complementary, for both types of clinical conditions. The reason for using each marker, sustained by relevant literature information, is provided in detail. With the constant development of immunophenotyping techniques in flow cytometry and related software, this work aims at providing useful guidelines to perform the most pertinent exploration at diagnosis and for follow-up, with the best cost benefit in diseases, the treatment of which has a strong impact on health systems.

Indexed as

Acute DiseaseHumansImmunophenotypingLeukemiaLymphoproliferative Disorders

Identifiers

PMID21252983
OpenAlexW1975806224

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.