Trial reportAIDS (London, England)2011
Mobile phone technologies improve adherence to antiretroviral treatment in a resource-limited setting: a randomized controlled trial of text message reminders.
Trial report in AIDS (London, England), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 504 papers, 27 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Single-blind, Randomized, Parallel Design Study to Assess the Effectiveness of SMS Reminders in Improving ART Adherence Among Adolescents Living With HIV in Nigeria (STARTA Trial-Adolescents)
PROvide MIner-friendly SErvices for Integrated TB/HIV Care in Lesotho Study (PROMISE Study)
Who cites it
504 citing papers in PubMed, 27 syntheses or guidelines pooled it.
- Effectiveness of Digital Health Interventions for Improving Antiretroviral Therapy Outcomes in People With HIV: Meta-Analysis and Trial Sequential Analysis of Randomized Controlled Trials.Journal of medical Internet research · 2026Pooled it
- Engagement With Conversational Agent-Enabled Interventions in Cardiometabolic Disease Self-Management: Systematic Review.JMIR mHealth and uHealth · 2025Pooled it
- Effect of short message service reminders in improving optimal antenatal care, skilled birth attendance and postnatal care in low-and middle-income countries: a systematic review and meta-analysis.BMC medical informatics and decision making · 2024Pooled it
- Digital Interventions for Managing Medication and Health Care Service Delivery in West Africa: Systematic Review.Journal of medical Internet research · 2024Pooled it
- Intervention strategies to improve adherence to treatment for selected chronic conditions in sub-Saharan Africa: a systematic review.Journal of the International AIDS Society · 2024Pooled it
- The impact of multiple-behavior HIV interventions as a function of regional disadvantages: An analysis of syndemics.Journal of consulting and clinical psychology · 2023Pooled it
- Effectiveness of mHealth on Adherence to Antiretroviral Therapy in Patients Living With HIV: Meta-analysis of Randomized Controlled Trials.JMIR mHealth and uHealth · 2023Pooled it
- Pooled it
- Effectiveness of eHealth Interventions for HIV Prevention and Management in Sub-Saharan Africa: Systematic Review and Meta-analyses.AIDS and behavior · 2022Pooled it
- Complex solutions for a complex problem: A meta-analysis of the efficacy of multiple-behavior interventions on change in outcomes related to HIV.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2021Pooled it
- Effectiveness of mobile text reminder in improving adherence to medication, physical exercise, and quality of life in patients living with HIV: a systematic review.BMC infectious diseases · 2021Pooled it
- Mobile phone-based interventions for improving adherence to medication prescribed for the primary prevention of cardiovascular disease in adults.The Cochrane database of systematic reviews · 2021Pooled it
- The effects of clinical decision support system for prescribing medication on patient outcomes and physician practice performance: a systematic review and meta-analysis.BMC medical informatics and decision making · 2021Pooled it
- Pooled it
- Routine Health Information System (RHIS) improvements for strengthened health system management.The Cochrane database of systematic reviews · 2020Pooled it
- Targeted client communication via mobile devices for improving sexual and reproductive health.The Cochrane database of systematic reviews · 2020Pooled it
- Electronic Health Interventions to Improve Adherence to Antiretroviral Therapy in People Living With HIV: Systematic Review and Meta-Analysis.JMIR mHealth and uHealth · 2019Pooled it
- Medication management support in diabetes: a systematic assessment of diabetes self-management apps.BMC medicine · 2019Pooled it
- A systematic review and meta-analysis in the effectiveness of mobile phone interventions used to improve adherence to antiretroviral therapy in HIV infection.BMC public health · 2019Pooled it
- Recent Interventions to Improve Retention in HIV Care and Adherence to Antiretroviral Treatment Among Adolescents and Youth: A Systematic Review.AIDS patient care and STDs · 2019Pooled it
444 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
objectiveThere is limited evidence on whether growing mobile phone availability in sub-Saharan Africa can be used to promote high adherence to antiretroviral therapy (ART). This study tested the efficacy of short message service (SMS) reminders on adherence to ART among patients attending a rural clinic in Kenya.
designA randomized controlled trial of four SMS reminder interventions with 48 weeks of follow-up.
methodsFour hundred and thirty-one adult patients who had initiated ART within 3 months were enrolled and randomly assigned to a control group or one of the four intervention groups. Participants in the intervention groups received SMS reminders that were either short or long and sent at a daily or weekly frequency. Adherence was measured using the medication event monitoring system. The primary outcome was whether adherence exceeded 90% during each 12-week period of analysis and the 48-week study period. The secondary outcome was whether there were treatment interruptions lasting at least 48 h.
resultsIn intention-to-treat analysis, 53% of participants receiving weekly SMS reminders achieved adherence of at least 90% during the 48 weeks of the study, compared with 40% of participants in the control group (P = 0.03). Participants in groups receiving weekly reminders were also significantly less likely to experience treatment interruptions exceeding 48 h during the 48-week follow-up period than participants in the control group (81 vs. 90%, P = 0.03).
conclusionThese results suggest that SMS reminders may be an important tool to achieve optimal treatment response in resource-limited settings.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.