Evidence map›Paper›PMID 21252066›Full record

ReviewArteriosclerosis, thrombosis, and vascular biology2011

Tissue factor-bearing microparticles and thrombus formation.

Jeffrey I Zwicker, Cameron C Trenor, Barbara C Furie, Bruce Furie

Abstract readReview
In one paragraph

Review in Arteriosclerosis, thrombosis, and vascular biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed.

  1. Dysregulation of Tissue Factor, Thrombin-Activatable Fibrinolysis Inhibitor, and Fibrinogen in Patients Undergoing Total Joint Arthroplasty.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis · 2017
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  17. Dysregulated haemostasis in thrombo-inflammatory disease.Clinical science (London, England : 1979) · 2022
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7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jeffrey I ZwickerDivision of Hemostasis, Harvard Medical School, Thrombosis Beth Israel Deaconess Medical Center, 330 Brookline Ave E/CLS 903, Boston, MA 02215, USA.
Cameron C Trenor
Barbara C Furie
Bruce Furie

Funding

Cancer, venous thromboembolic disease and tissue factor-bearing microparticlesR01HL095084 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI FURIE, BRUCE · 2008 to 2012
$2.1M
Bloodborne tissue factor-bearing microparticles in Trousseau's syndromeK23HL084052 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI ZWICKER, JEFFREY · 2007 to 2011
$747k
NHLBI NIH HHS K23 HL084052NHLBI NIH HHS R01 HL095084
6 · The paper itself

Abstract

Blood microparticles are vesicular structures with a diameter of 100 to 1000 nm that are present in the blood of normal subjects and in patients with various diseases. These microparticles are derived from cells that circulate in the blood and cells associated with the blood vessel wall. Microparticle membranes retain the protein receptors of their parent cells and may retain RNAs and other cytosolic content. On the basis of surface protein expression, microparticles are known to be derived from platelets, granulocytes, monocytes, endothelial cells, smooth muscle cells, and tumor cells. Only a subpopulation of these microparticles expresses tissue factor.

Indexed as

Blood CoagulationAnimalsCell-Derived MicroparticlesHumansParticle SizeThromboplastinThrombosisThromboplastin

Identifiers

PMID21252066
PMCPMC6112768

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.