Evidence map›Paper›PMID 21251566›Full record

ArticleDiagnostic microbiology and infectious disease2011

Nontypeable Streptococcus pneumoniae as an otopathogen.

Qingfu Xu, Ravinder Kaur, Janet R Casey, Vishakha Sabharwal, Stephen Pelton, Michael E Pichichero

Abstract readCase Reports
In one paragraph

Article in Diagnostic microbiology and infectious disease, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. An abundance ofMicrobiology (Reading, England) · 2025
    Article
  3. Article
  4. Article
  5. Characterization of MSlys, the endolysin ofBiotechnology reports (Amsterdam, Netherlands) · 2020
    Article
  6. The Best of All Worlds:Microorganisms · 2019
    Review
  7. Panel 4: Report of the Microbiology Panel.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2017
    Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Qingfu XuRochester General Hospital Research Institute, Rochester, NY 14621, USA.
Ravinder Kaur
Janet R Casey
Vishakha Sabharwal
Stephen Pelton
Michael E Pichichero

Funding

NTHi Immunity in Young ChildrenR01DC008671 · NIDCD · UNIVERSITY OF ROCHESTER · PI PICHICHERO, MICHAEL E · 2007 to 2016
$5.8M
NIDCD NIH HHS R01 DC008671NIDCD NIH HHS R01DC008671-01A2
6 · The paper itself

Abstract

Among 34 Streptococcus pneumoniae (Spn) sequential isolates from middle ear fluid, we found a case of a nontypeable S. pneumoniae (NT-Spn) in a child with acute otitis media (AOM). The strain was pneumolysin PCR positive and capsule gene PCR negative. Virulence of the NT-Spn was confirmed in a chinchilla model of AOM.

Indexed as

Acute DiseaseAnimalsBacterial ProteinsBacterial Typing TechniquesChinchillaHumansInfantMaleMultilocus Sequence TypingOtitis MediaPhylogenyStreptococcus pneumoniaeStreptolysinsBacterial ProteinsplY protein, Streptococcus pneumoniaeStreptolysins

Identifiers

PMID21251566
PMCPMC3897191

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.