ArticleCanadian journal of surgery. Journal canadien de chirurgie2011
Uncrossmatched blood transfusions for trauma patients in the emergency department: incidence, outcomes and recommendations.
Article in Canadian journal of surgery. Journal canadien de chirurgie, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 37 citations in OpenAlex.
- Emergency transfusion of uncross-matched O-type red blood cells in patients with severe pelvic fracture: a multi-center propensity score-weighted analysis.World journal of emergency medicine · 2026Article
- The epidemiology of overtransfusion of red cells in trauma resuscitation patients in the context of a mature massive transfusion protocol.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022Article
- Experience with uncrossmatched blood refrigerator in emergency department.Trauma surgery & acute care open · 2018Article
- Pre-hospital transfusion of packed red blood cells in 147 patients from a UK helicopter emergency medical service.Scandinavian journal of trauma, resuscitation and emergency medicine · 2017Article
- Mortality outcomes in trauma patients undergoing prehospital red blood cell transfusion: a systematic literature review.International journal of burns and trauma · 2017Review
- Persistence of elevated plasma CXCL8 concentrations following red blood cell transfusion in a trauma cohort.Shock (Augusta, Ga.) · 2012Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEarly transfusion of blood products for severely injured patients can improve volume depletion, acidosis, dilution and coagulopathy. There is concern that some patients are unnecessarily exposed to the risks of emergent transfusion with uncrossmatched red blood cell products (URBC) in the emergency department (ED). The goal of this study was to evaluate the transfusion practices in our ED among all patients who received URBC.
methodsWe analyzed all injured patients transfused at least 1 URBC in the ED at a level-1 trauma centre between Jan. 15, 2007, and Jan. 14, 2008. Demographics, injuries and outcomes were reported. We used standard statistical methodology.
resultsAt least 1 URBC product was transfused into 153 patients (5% of all patients, mean 2.6 products) in the ED (median Injury Severity Score [ISS] 28; hemodynamic instability 94%). Sixty-four percent of patients proceeded to an emergent operation and 17% required massive transfusion. The overall mortality rate was 45%, which increased to 52% and 100% in patients who received 4 and 5 or more URBC products, respectively. Nonsurvivors had a higher median ISS (p=0.017), received more URBC in the ED (p=0.006) and possessed more major vascular injuries (p<0.001). Among nonsurvivors, 67% died of uncontrollable hemorrhage. Unnecessary URBC transfusions in the ED occurred in 7% of patients.
conclusionOvertransfusion was minimal based on clinical acumen triggers. Early transfer of patients receiving URBC products in the ED to the operating room, intensive care unit or angiography suite for ongoing resuscitation and definitive hemorrhage control must be strongly considered.
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