Evidence map›Paper›PMID 21250917›Full record

ArticleJournal of neurotrauma2011

Diffusion tensor imaging of incentive effects in prospective memory after pediatric traumatic brain injury.

Stephen R McCauley, Elisabeth A Wilde, Erin D Bigler, Zili Chu, Ragini Yallampalli, Margaret B Oni, Trevor C Wu, Marco A Ramos, Claudia Pedroza, Ana C Vásquez and 2 more

Abstract read
In one paragraph

Article in Journal of neurotrauma, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
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  7. Article
  8. Article
  9. Neuroimaging of the Injured Pediatric Brain: Methods and New Lessons.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2018
    Review
  10. Article
  11. Diffusion MRI in pediatric brain injury.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2017
    Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
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  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Stephen R McCauleyPhysical Medicine and Rehabilitation Alliance of Baylor College of Medicine and University of Texas-Houston Medical School, Houston, Texas, USA. mccauley@bcm.edu
Elisabeth A Wilde
Erin D Bigler
Zili Chu
Ragini Yallampalli
Margaret B Oni
Trevor C Wu
Marco A Ramos
Claudia Pedroza
Ana C Vásquez
Jill V Hunter
Harvey S Levin

Funding

NEUROBEHAVIORAL OUTCOME OF HEAD INJURY IN CHILDRENR01NS021889 · NINDS · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI HANTEN, GERRI RAE, LEVIN, HARVEY · 1985 to 2013
$10.4M
Prospective Memory in Normal and Head-Injured ChildrenK23HD040896 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI MCCAULEY, STEPHEN RYAN · 2002 to 2005
$500k
NICHD NIH HHS K23 HD-40896NINDS NIH HHS NS-21889
6 · The paper itself

Abstract

Few studies exist investigating the brain-behavior relations of event-based prospective memory (EB-PM) impairments following traumatic brain injury (TBI). To address this, children with moderate-to-severe TBI performed an EB-PM test with two motivational enhancement conditions and underwent concurrent diffusion tensor imaging (DTI) at 3 months post-injury. Children with orthopedic injuries (OI; n=37) or moderate-to-severe TBI (n=40) were contrasted. Significant group differences were found for fractional anisotropy (FA) and apparent diffusion coefficient for orbitofrontal white matter (WM), cingulum bundles, and uncinate fasciculi. The FA of these WM structures in children with TBI significantly correlated with EB-PM performance in the high, but not the low motivation condition. Regression analyses within the TBI group indicated that the FA of the left cingulum bundle (p=0.003), left orbitofrontal WM (p<0.02), and left (p<0.02) and right (p<0.008) uncinate fasciculi significantly predicted EB-PM performance in the high motivation condition. We infer that the cingulum bundles, orbitofrontal WM, and uncinate fasciculi are important WM structures mediating motivation-based EB-PM responses following moderate-to-severe TBI in children.

Indexed as

MotivationNerve Fibers, MyelinatedAdolescentBrainBrain InjuriesBrain MappingChildDiffusion Tensor ImagingHumansImage Processing, Computer-AssistedInjury Severity ScoreMagnetic Resonance ImagingMemoryNeuropsychological TestsRegression Analysis

Identifiers

PMID21250917
PMCPMC3070141

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.