Evidence map›Paper›PMID 21249481›Full record

ArticleCurrent oncology reports2011

Oral dysplasia: biomarkers, treatment, and follow-up.

Paul Nankivell, Hisham Mehanna

Abstract read
PubMed Publisher
In one paragraph

Article in Current oncology reports, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 57 citations in OpenAlex.

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  13. Oral premalignancy: the roles of early detection and chemoprevention.Otolaryngologic clinics of North America · 2013
    Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Paul NankivellInstitute of Head and Neck Studies and Education (InHANSE), University Hospitals Coventry and Warwickshire, Clifford Bridge Road, Coventry, CV2 2DX, UK.
Hisham Mehanna
University Hospitals Coventry and Warwickshire NHS Trust · GB

Funding

Cancer Research UK 12617
6 · The paper itself

Abstract

Dysplasia affecting the oral mucosa has a malignant potential. The options for treatment of oral dysplasia are limited. Surgery remains the mainstay of management, with no strong evidence for medical treatments currently available. Histological grading alone does not accurately predict which dysplastic lesions will progress to cancer, which poses the clinician with difficult decisions regarding the most appropriate treatment and may lead to some patients being overtreated, with potentially unnecessary morbidity. The use of biomarkers may help to improve prediction of which cases are likely to transform. The efficacy of individual markers for prediction will be discussed in this paper. There is also a lack of consensus on the optimal frequency and duration of follow-up for patients with oral dysplasia.

Indexed as

Biomarkers, TumorDisease ProgressionHumansMouth DiseasesMouth MucosaMouth NeoplasmsPrecancerous ConditionsBiomarkers, Tumor

Identifiers

PMID21249481
OpenAlexW2053837661

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.