ArticleInfectious agents and cancer2011
Distribution of high and low risk HPV types by cytological status: a population based study from Italy.
Article in Infectious agents and cancer, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 31 citations in OpenAlex.
- Human Papillomavirus Infection and Cervical Cytology Among Vulnerable Women in Rome, Italy.Journal of clinical medicine · 2026Article
- Potential mechanisms of ZiGongDing in treating HPV-induced cervical intraepithelial neoplasia: a network pharmacology and experimental verification study.Naunyn-Schmiedeberg's archives of pharmacology · 2025Article
- Comparison of the Immune Responses to Different Formulations of BC02-Adjuvanted HPV Types 16 and 18 Bivalent Vaccines in Mice.Vaccines · 2023Article
- Impact of HR-HPV infection on oncological outcomes in early cervical cancer.Frontiers in oncology · 2023Article
- Construction and immune effect of an HPV16/18/58 trivalent therapeutic adenovirus vector vaccine.Infectious agents and cancer · 2022Article
- Prevalence of "unclassified" HPV genotypes among women with abnormal cytology.Infectious agents and cancer · 2018Article
- Screening women for cervical cancer carcinoma with a HPV mRNA test: first results from the Venice pilot program.British journal of cancer · 2016Article
- Evaluation of careHPV, Cervista Human Papillomavirus, and Hybrid Capture 2 Methods in Diagnosing Cervical Intraepithelial Neoplasia Grade 2+ in Xinjiang Uyghur Women.The oncologist · 2016Article
- A high performance prediction of HPV genotypes by Chaos game representation and singular value decomposition.BMC bioinformatics · 2015Article
- Follow-up of women with atypical squamous cells cannot exclude high-grade squamous intraepithelial lesions (ASC-H).Sao Paulo medical journal = Revista paulista de medicina · 2014Article
- High prevalence of hpv multiple genotypes in women with persistent chlamydia trachomatis infection.Infectious agents and cancer · 2014Article
- Human papillomavirus types distribution in eastern Sicilian females with cervical lesions. A correlation with colposcopic and histological findings.Pathology oncology research : POR · 2013Article
- A cross-sectional study to estimate high-risk human papillomavirus prevalence and type distribution in Italian women aged 18-26 years.BMC infectious diseases · 2013Article
- HPV Infection in a Cohort of HIV-Positive Men and Women: Prevalence of Oncogenic Genotypes and Predictors of Mucosal Damage at Genital and Oral Sites.Journal of sexually transmitted diseases · 2013Article
- Prevalence of low-risk HPV types and genital warts in women born 1988/89 or 1983/84 -results of WOLVES, a population-based epidemiological study in Wolfsburg, Germany.BMC infectious diseases · 2012Article
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Authors and funding
14 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHPV type distribution by cytological status represents useful information to predict the impact of mass vaccination on screening programs.
methodswomen aged from 25 to 64 who attended cervical cancer screening in five different Italian regions were tested for HPV infection with Hybrid Capture II (HCII) low and high risk probes. Women repeating Pap-test upon unsatisfactory or positive results, or as a post-treatment and post-colposcopy follow-up analysis, were excluded from our study. High risk (HR) HPV positive samples were typed using GP5+/GP6+ primed PCR, followed by Reverse Line Blot for 18 high/intermediate risk HPV types, while low risk (LR) HPV positive samples were tested with type specific primers for HPV6 and HPV11.
results3410 women had a valid HCII and Pap-test. The prevalence of HR and LR infections was 7.0% and 3.6%, 29.1% and 13.7%, 68.1% and 31.9%, 60.0% and 0.0%, 65.0% and 12.0%, for negative, ASC-US, L-SIL, ASC-H and H-SIL cytology, respectively. The fraction of ASC-US+ cytology due to HPV 16 and 18 ranged from 11.2 (HPV 16/18 alone) to 15.4% (including HPV 16/18 in co-infection with other virus strains), and that due to HPV 6 and 11 ranged from 0.2% (HPV 6/11 alone) to 0.7% (including HPV 6/11 in co-infection with other LR virus strains).
conclusionsmass vaccination with bivalent or quadrivalent HPV vaccine would modestly impact on prevalence of abnormal Pap-test in screening.
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