Evidence map›Paper›PMID 21247316›Full record

ReviewThe New England journal of medicine2011

Necrotizing enterocolitis.

Josef Neu, W Allan Walker

2 registry-linked trialsAbstract readReview
In one paragraph

Review in The New England journal of medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 1,127 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,127citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04074824 active not recruitingnot on this mapstarted 2018, after this paper: background citation

A Genome-Wide Association Study on Chinese Preterm Neonates and Identification of Functional Variants for Susceptibility to Necrotising Enterocolitis

TypeobservationalSponsorChinese University of Hong KongRan2018 to 2026Enrolled310ConditionsNeonatal Disease, Necrotizing Enterocolitis
NCT05279664 phase2active not recruitingnot on this mapstarted 2023, after this paper: background citation

RIC-NEC Phase II Feasibility Randomized Controlled Trial: Remote Ischemic Conditioning in Necrotizing Enterocolitis

TypeinterventionalSponsorThe Hospital for Sick ChildrenRan2023 to 2026Enrolled78ConditionsNecrotizing EnterocolitisArmsRemote ischemic conditioning (RIC) + Standard of Care for NEC, Standard of Care for NEC
3 · Its place in the literature

Who cites it

1,127 citing papers in PubMed, 7 syntheses or guidelines pooled it.

  1. Pooled it
  2. Developing a prioritized research agenda for necrotizing enterocolitis.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Pooled it
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  16. The fetoneonatology fellowship: a unified subspecialty for the fetal-neonatal continuum.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Review
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1,067 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Josef NeuDepartment of Pediatrics, University of Florida, Gainesville, USA.
W Allan Walker

Funding

ROLE OF DIETARY CONSTITUENTS ON GENE EXPRESSION IN INTESTINAL EPITHELIUMP30DK040561 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Elizabeth Austen Lawson, Takara Leah Stanley · 1994 to 2026
$31.6M
Intestinal Microecology, Inflammatory Markers and Necrotizing EnterocolitisR01HD059143 · NICHD · UNIVERSITY OF FLORIDA · PI NEU, JOSEF · 2009 to 2013
$1.7M
NICHD NIH HHS R01 HD059143NIDDK NIH HHS P30 DK040561
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Enterocolitis, NecrotizingInfant, Premature, DiseasesDiagnosis, DifferentialDrainageHumansInfant, NewbornInfant, PrematureInflammationIntestinesPrebioticsProbioticsPrebiotics

Identifiers

PMID21247316
PMCPMC3628622

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.