Evidence map›Paper›PMID 21247088›Full record

ArticleThe journal of physical chemistry. B2011

Comment on "urea-mediated protein denaturation: a consensus view".

Ruhong Zhou, Jingyuan Li, Lan Hua, Zaixing Yang, B J Berne

Open access · greenAbstract readComment
In one paragraph

Article in The journal of physical chemistry. B, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 39 citations in OpenAlex.

  1. First Hydration Shell Integrity: Key to Protein Stability.Journal of the American Chemical Society · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. A hypothesis to reconcile the physical and chemical unfolding of proteins.Proceedings of the National Academy of Sciences of the United States of America · 2015
    Article
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Ruhong ZhouIBM Thomas J. Watson Research Center, Yorktown Heights, New York 10598, USA. ruhongz@us.ibm.com
Jingyuan Li
Lan Hua
Zaixing Yang
B J Berne
IBM Research - Thomas J. Watson Research Center · USColumbia University · USUniversity of California, San Francisco · USZhejiang University · CN

Funding

MODELING HYDROPHOBIC &HYDROPHILIC INTERACTIONSR01GM043340 · NIGMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI BERNE, BRUCE J · 1991 to 2015
$3.8M
NIGMS NIH HHS GM44330NIGMS NIH HHS R01 GM043340
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

gamma-CrystallinsMuramidaseProtein DenaturationStatic ElectricityThermodynamicsUbiquitinUreagamma-CrystallinsMuramidaseUbiquitinUrea

Identifiers

PMID21247088
PMCPMC3050030
OpenAlexW2094026650

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.