Evidence map›Paper›PMID 21246663›Full record

ReviewDevelopmental dynamics : an official publication of the American Association of Anatomists2011

Vertebrate intestinal endoderm development.

Jason R Spence, Ryan Lauf, Noah F Shroyer

Abstract readReview
In one paragraph

Review in Developmental dynamics : an official publication of the American Association of Anatomists, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 105 papers.

0numbers the graph read from it
0cells of the map it votes in
105citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

105 citing papers in PubMed.

  1. Primary Cultures of Fetal Epithelial Progenitors.Methods in molecular biology (Clifton, N.J.) · 2027
    Article
  2. Regional organization of nutrient absorption across the small intestine.Nature reviews. Gastroenterology & hepatology · 2026
    Review
  3. Endoderm differentiates into a transient epidermis in the mouse perineum.Developmental dynamics : an official publication of the American Association of Anatomists · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. The developmental mechanics of divergent buckling patterns in the chick gut.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review

45 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jason R Spence
Ryan Lauf
Noah F Shroyer

Funding

TRAINING IN DEVELOPMENTAL AND PERINATAL ENDOCRINOLOGYT32HD007463 · NICHD · CINCINNATI CHILDRENS HOSP MED CTR · PI HANDWERGER, STUART · 1994 to 2010
$1.5M
The role of ATOH1 as a tumor suppressor in colorectal cancerR01CA142826 · NCI · CINCINNATI CHILDRENS HOSP MED CTR · PI SHROYER, NOAH FREEMAN · 2010 to 2014
$1.5M
SPDEF in intestinal differentiation.R03DK084167 · NIDDK · CINCINNATI CHILDRENS HOSP MED CTR · PI SHROYER, NOAH FREEMAN · 2009 to 2010
$151k
Developmental Paradigms to Direct Human Endoderm into Foregut LineageF32DK083202 · NIDDK · CINCINNATI CHILDRENS HOSP MED CTR · PI SPENCE, JASON · 2008 to 2010
$83k
NCI NIH HHS R01 CA142826NICHD NIH HHS T32 HD007463NICHD NIH HHS T32 HD07463NIDDK NIH HHS F32 DK083202NIDDK NIH HHS F32 DK83202-01NIDDK NIH HHS R03 DK084167
6 · The paper itself

Abstract

The endoderm gives rise to the lining of the esophagus, stomach and intestines, as well as associated organs. To generate a functional intestine, a series of highly orchestrated developmental processes must occur. In this review, we attempt to cover major events during intestinal development from gastrulation to birth, including endoderm formation, gut tube growth and patterning, intestinal morphogenesis, epithelial reorganization, villus emergence, as well as proliferation and cytodifferentiation. Our discussion includes morphological and anatomical changes during intestinal development as well as molecular mechanisms regulating these processes.

Indexed as

AnimalsCell DifferentiationEndodermHumansIntestinal MucosaIntestinesMesodermVertebrates

Identifiers

PMID21246663
PMCPMC3079549

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.