Evidence map›Paper›PMID 21246530›Full record

ArticleCancer2011

Occupational outcomes of adult childhood cancer survivors: A report from the childhood cancer survivor study.

Anne C Kirchhoff, Kevin R Krull, Kirsten K Ness, Elyse R Park, Kevin C Oeffinger, Melissa M Hudson, Marilyn Stovall, Leslie L Robison, Thomas Wickizer, Wendy Leisenring

Registry-linked trialAbstract read
In one paragraph

Article in Cancer, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03148080 (Work Ability in Young Adult Survivors), which is not on this map. Cited by 55 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 3 pooled it
6.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03148080 completednot on this mapstarted 2018, after this paper: background citation

Work Ability in Young Adult Survivors (WAYS)

TypeobservationalSponsorWake Forest University Health SciencesRan2018 to 2022Enrolled214ConditionsCancer SurvivorArmsCognitive Assessment, Questionnaire Administration
3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 3 syntheses or guidelines pooled it, 111 citations in OpenAlex.

  1. Pooled it
  2. Unemployment Following Childhood Cancer.Deutsches Arzteblatt international · 2017
    Pooled it
  3. Pooled it
  4. Review
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  9. Educational and occupational aspirations of adolescent and young adult cancer survivors: a qualitative analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Anne C KirchhoffPublic Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA. akirchho@fhcrc.org
Kevin R Krull
Kirsten K Ness
Elyse R Park
Kevin C Oeffinger
Melissa M Hudson
Marilyn Stovall
Leslie L Robison
Thomas Wickizer
Wendy Leisenring
St. Jude Children's Research Hospital · USFred Hutch Cancer Center · USMassachusetts General Hospital · USMemorial Sloan Kettering Cancer Center · USThe Ohio State University · USThe University of Texas MD Anderson Cancer Center · US

Funding

Viral Vector Technology (VVTSR)P30CA021765 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI SUZANNE J. BAKER · 1985 to 2026
$166.9M
Mach-LETSGO: Machine-LEarning of Treatment, Survey, and Genetics towards Obtaining Correct Classification of Chronic Conditions in Adult Survivors in the Childhood Cancer Survivor Study - CCSS SupplU24CA055727 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Gregory Armstrong · 1999 to 2026
$96.7M
NCI NIH HHS P30 CA021765NCI NIH HHS U24 CA055727NCI NIH HHS U24 CA55727
6 · The paper itself

Abstract

backgroundThe authors examined whether survivors from the Childhood Cancer Survivor Study were less likely to be in higher-skill occupations than a sibling comparison and whether certain survivors were at higher risk for lower-skill jobs.

methodsThe authors created 3 mutually exclusive occupational categories for participants aged ≥ 25 years: Managerial/Professional, Nonphysical Service/Blue Collar, and Physical Service/Blue Collar. The authors examined currently employed survivors (4845) and their siblings (1727) in multivariable generalized linear models to evaluate the likelihood of being in 1 of the 3 occupational categories. Multinomial logistic regression was used among all participants to examine the likelihood of these outcomes compared to being unemployed (survivors, 6671; siblings, 2129). Multivariable linear models were used to assess survivor occupational differences by cancer-  and treatment-related variables. Personal income was compared by occupation.

resultsEmployed survivors were less often in higher-skilled Managerial/Professional occupations (relative risk, 0.93; 95% confidence interval 0.89-0.98) than their siblings. Survivors who were black, were diagnosed at a younger age, or had high-dose cranial radiation were less likely to hold Managerial/Professional occupations than other survivors. In multinomial models, female survivors' likelihood of being in full-time Managerial/Professional occupations (27%) was lower than male survivors (42%) and female (41%) and male (50%) siblings. Survivors' personal income was lower than siblings within each of the 3 occupational categories in models adjusted for sociodemographic variables.

conclusionsAdult childhood cancer survivors are employed in lower-skill jobs than siblings. Survivors with certain treatment histories are at higher risk for lower-skill jobs and may require vocational assistance throughout adulthood.

Indexed as

NeoplasmsOccupationsSurvivorsAdultAgedEducational StatusEmploymentFemaleHumansIncomeMaleMiddle AgedRacial GroupsSex FactorsSiblingsSocial Conditions

Identifiers

PMID21246530
PMCPMC3547616
OpenAlexW1976500166

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.