Trial reportEuropean journal of applied physiology2011
Modulation of reflex responses in activated ankle dorsiflexors differs in healthy young and elderly subjects.
Trial report in European journal of applied physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 28 citations in OpenAlex.
- Wobble-board dynamics as a scalable assay of long-latency reflex function in aging.GeroScience · 2026Article
- Wobble-board instability re-orthogonalizes postural geometry in older adults through exogenous constraint.GeroScience · 2026Article
- Angular distribution of fractal temporal correlations supports adaptive responses to wobble board instability.Journal of the Royal Society, Interface · 2025Article
- The neuromechanics of the soleus for fall prevention in aging.Frontiers in physiology · 2025Review
- Influence of aging and task-related activation on descending cortical modulation of spinal sensorimotor circuitry.Aging brain · 2025Article
- Selective engagement of long-latency reflexes in postural control through wobble board training.Scientific reports · 2024Article
- A single sequence of intermittent hypoxia does not alter stretch reflex excitability in able-bodied individuals.Experimental physiology · 2024Article
- Revisiting the use of Hoffmann reflex in motor control research on humans.European journal of applied physiology · 2023Review
- Facilitation-inhibition control of motor neuronal persistent inward currents in young and older adults.The Journal of physiology · 2022Article
- Age-Related Changes in Accuracy and Speed of Lateral Crossing Motion: Focus on Stepping from Leaning Position.International journal of environmental research and public health · 2022Article
- Effects of voluntary contraction on the soleus H-reflex of different amplitudes in healthy young adults and in the elderly.Frontiers in human neuroscience · 2022Article
- The variability of isokinetic ankle strength is different in healthy older men and women.Clinics (Sao Paulo, Brazil) · 2022Article
- Age-related changes in leg proprioception: implications for postural control.Journal of neurophysiology · 2019Review
- Fatigue-induced adjustment in antagonist coactivation by old adults during a steadiness task.Journal of applied physiology (Bethesda, Md. : 1985) · 2016Article
- Neural Activation During Submaximal Contractions Seems More Reflective of Neuromuscular Ageing than Maximal Voluntary Activation.Frontiers in aging neuroscience · 2016Article
- Cognitive demand does not influence the responsiveness of homonymous Ia afferents pathway during postural dual task in young and elderly adults.European journal of applied physiology · 2014Article
- Aging causes a reorganization of cortical and spinal control of posture.Frontiers in aging neuroscience · 2014Review
- Timing of muscle response to a sudden leg perturbation: comparison between adolescents and adults with Down syndrome.PloS one · 2013Article
- Age-related influence of vision and proprioception on Ia presynaptic inhibition in soleus muscle during upright stance.The Journal of physiology · 2012Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
During voluntary contractions, motor neurone activity is modulated by descending input and sensory feedback. Impaired excitatory afferent feedback with ageing may, therefore, alter motor control. This study investigated the age-related changes in afferent feedback through the recording of reflex responses during voluntary muscle activation. Short- and long-latency components of the stretch reflex and Hoffmann reflex (H-reflex) were recorded during voluntary contractions (10% of maximal voluntary contraction; MVC) of the ankle dorsiflexor muscles of young and elderly adults (≥70 years). Furthermore, the modulation of spinal reflex excitability was analyzed at different torque levels (10-50% MVC). The short-latency stretch reflex and the H-reflex areas were similar in the two age groups at 10% MVC whereas the area of the long-latency component of the stretch reflex augmented with ageing (P < 0.05). However, the area of the H-reflex increased linearly with the level of contraction up to 50% MVC in young adults, whereas it slightly increased to 30% MVC and plateaued thereafter in elderly adults. The absence of age-related changes in the short-latency stretch reflex and H-reflex areas suggests that the reflex circuitry and the sensitivity of the muscle spindles are not substantially affected by ageing. The modest increase in the H-reflex area with the contraction intensity in elderly adults, however, indicates that the modulation of afferent feedback is reduced with advancing age. This observation, associated with a greater long-latency stretch reflex, suggests that elderly adults rely more on central than peripheral mechanisms to regulate motor output of the dorsiflexor muscles.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.