Evidence map›Paper›PMID 21246000›Full record

ArticleWorld journal of gastroenterology2011

Risk factors for hilar cholangiocarcinoma: a case-control study in China.

Wen-Ke Cai, Hui Sima, Ben-Dong Chen, Guang-Shun Yang

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastroenterology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 6 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 6 syntheses or guidelines pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Viral hepatitis B and C infections increase the risks of intrahepatic and extrahepatic cholangiocarcinoma: Evidence from a systematic review and meta-analysis.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2020
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  7. The Role of microRNAs in Cholangiocarcinoma.International journal of molecular sciences · 2021
    Review
  8. Complete laparoscopic radical resection of hilar cholangiocarcinoma: technical aspects and long-term results from a single center.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Wen-Ke CaiDepartment of Biliary Surgery II, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai 200438, China. caiwenke002@126.com
Hui Sima
Ben-Dong Chen
Guang-Shun Yang
Second Military Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo study the association between hilar cholangiocarcinoma (HC) and pre-existing medical conditions.

methodsThree hundred and thirteen HC patients admitted to the Eastern Hepatobiliary Surgery Hospital (Shanghai, China) in 2000-2005 and 608 healthy controls were enrolled in this study. Association between HC and pre-existing medical conditions was studied with their adjusted odds ratio (OR) calculated by logistic regression analysis.

resultsThe prevalence of choledocholithiasis (adjusted OR = 2.704, P = 0.039), hepatolithiasis (adjusted OR = 3.278, P = 0.018), cholecystolithiasis (adjusted OR = 4.499, P < 0.0001), cholecystectomy (adjusted OR = 7.012, P = 0.004), biliary ascariasis (adjusted OR = 7.188, P = 0.001), liver fluke (adjusted OR = 10.088, P = 0.042) and liver schistosomiasis (adjusted OR = 9.913, P = 0.001) was higher in HC patients than in healthy controls.

conclusionBiliary tract stone disease (choledocholithiasis, hepatolithiasis, cholecystolithiasis) and parasitic liver disease (biliary ascariasis, liver fluke, liver schistosomiasis) are the risk factors for HC in Chinese population.

Indexed as

AdultAgedAged, 80 and overAnimalsAscariasisBile Duct NeoplasmsCase-Control StudiesChinaCholangiocarcinomaCholecystectomyCholecystolithiasisCholedocholithiasisFasciola hepaticaFemaleHumansLithiasisCholedocholithiasisHepatitis B virusHepatitis C virusHilar cholangiocarcinomaLiver fluke

Identifiers

PMID21246000
PMCPMC3020381
OpenAlexW2100313728

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.