Evidence map›Paper›PMID 21245997›Full record

ArticleWorld journal of gastroenterology2011

18F-fluorodeoxyglucose positron emission tomography in the diagnosis of small pancreatic cancer.

Keiichi Okano, Keitaro Kakinoki, Shintaro Akamoto, Masanobu Hagiike, Hisashi Usuki, Yuka Yamamoto, Yoshihiro Nishiyama, Yasuyuki Suzuki

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastroenterology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 45 citations in OpenAlex.

  1. Review
  2. [American journal of nuclear medicine and molecular imaging · 2024
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  7. Article
  8. Challenges in diagnosis of pancreatic cancer.World journal of gastroenterology · 2018
    Review
  9. Review
  10. Article
  11. Diagnostic strategies for early pancreatic cancer.Journal of gastroenterology · 2015
    Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. State-of-the-art PET/CT of the pancreas: current role and emerging indications.Radiographics : a review publication of the Radiological Society of North America, Inc
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Keiichi OkanoDepartment of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, Kagawa 761-0793, Japan. kokano@kms.ac.jp
Keitaro Kakinoki
Shintaro Akamoto
Masanobu Hagiike
Hisashi Usuki
Yuka Yamamoto
Yoshihiro Nishiyama
Yasuyuki Suzuki
Kagawa University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate the role of (18)F-fluorodeoxyglucose positron emission tomography (FDG-PET) in the diagnosis of small pancreatic cancer.

methodsThis study involved 31 patients with proven invasive ductal cancer of the pancreas. The patients were divided into 3 groups according to the maximum diameter of the tumor: TS1 (maximum tumor size ≤ 2.0 cm), TS2 (> 2.0 cm and ≤ 4.0 cm) or TS3-4 (> 4.0 cm). The relationships between the TS and various diagnostic tools, including FDG-PET with dual time point evaluation, were analyzed.

resultsThe tumors ranged from 1.3 to 11.0 cm in diameter. Thirty of the 31 patients (97%) had a positive FDG-PET study. There were 5 patients classified as TS1, 15 as TS2 and 11 as TS3-4. The sensitivity of FDG-PET, computed tomography (CT) and magnetic resonance imaging (MRI) were 100%, 40%, 0% in TS1, 93%, 93%, 89% in TS2 and 100%, 100%, 100% in TS3-4. The sensitivity of FDG-PET was significantly higher in comparison to CT and MRI in patients with TS1 (P < 0.032). The mean standardized uptake values (SUVs) did not show a significant difference in relation to the TS (TS1: 5.8 ± 4.5, TS2: 5.7 ± 2.2, TS3-4: 8.2 ± 3.9), respectively. All the TS1 tumors (from 13 to 20 mm) showed higher SUVs in FDG-PET with dual time point evaluation in the delayed phase compared with the early phase, which suggested the lesions were malignant.

conclusionThese results indicate that FDG-PET with dual time point evaluation is a useful modality for the detection of small pancreatic cancers with a diameter of less than 20 mm.

Indexed as

AdultAgedAged, 80 and overFemaleFluorodeoxyglucose F18HumansMagnetic Resonance ImagingMaleMedical OncologyMiddle AgedPancreatic NeoplasmsPositron-Emission TomographyQuality of LifeRadiopharmaceuticalsRetrospective StudiesSensitivity and SpecificityFluorodeoxyglucose F18Radiopharmaceuticals18F-fluorodeoxyglucoseDual time point evaluationDuctal carcinomaPancreasPancreatic cancerPositron emission tomography

Identifiers

PMID21245997
PMCPMC3020378
OpenAlexW2131772745

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.