Evidence map›Paper›PMID 21245888›Full record

ArticleEuropean journal of clinical nutrition2011

Sunlight is an important determinant of vitamin D serum concentrations in cystic fibrosis.

E Robberecht, S Vandewalle, C Wehlou, J-M Kaufman, J De Schepper

Open access · goldAbstract readComparative Study
PubMed Publisher
In one paragraph

Article in European journal of clinical nutrition, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 3 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Vitamin D levels in systemic sclerosis patients: a meta-analysis.Drug design, development and therapy · 2017
    Pooled it
  4. Article
  5. A Clinician's guide to vitamin D supplementation for patients with cystic fibrosis.Journal of clinical & translational endocrinology · 2021
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Treatment of vitamin D deficiency in cystic fibrosis.The Journal of steroid biochemistry and molecular biology · 2016
    Review
  12. Vitamin D in the new millennium.Current osteoporosis reports · 2012
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

E RobberechtCF Centre Ghent University Hospital, Ghent, Belgium. eddy.robberecht@Uzgent.be
S Vandewalle
C Wehlou
J-M Kaufman
J De Schepper
Ghent University Hospital · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesThe increase of bone disease in adult cystic fibrosis (CF) patients is partly attributed to inadequate serum concentrations of 25-OH cholecalciferol (25 (OH) D) blamed on fat malabsorption. Based on physiological, clinical and biochemical observations this pathogenesis is debatable. The objective was to ascertain the relative importance of different 25 (OH) D sources. SUBJECTS/

methodsOver 4 consecutive years, 474 annual 25 (OH) D serum concentrations from 141 CF patients of all ages were compared with values of healthy peers and weighed against annual ultraviolet B (UVB) exposure.

resultsRanked per month, 25 (OH) D concentrations depicted a curve strikingly parallel to the amount of UVB exposure in the preceding months. A significant difference exists between 25 (OH) D concentrations in the 'Months with high UVB exposure' (May-October) and the 'Months with low UVB exposure' (November-April) but not with healthy controls in the same period.

conclusions25 (OH) D concentrations clearly respond to the amount of sunshine in preceding months. They are not clearly influenced by daily oral supplements of 800 IU of cholecalciferol. Sun exposure should be encouraged, and the recommended dosage of oral supplements increased.

Indexed as

SunlightAdolescentAdultCalcifediolChildChild, PreschoolCystic FibrosisFemaleHumansInfantMaleSeasonsVitamin DVitamins25-hydroxyvitamin DCalcifediolVitamin DVitamins

Identifiers

PMID21245888
OpenAlexW2076363194

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.