ArticleMolecules (Basel, Switzerland)2011
Schistosomicidal activity of the essential oil of Ageratum conyzoides L. (Asteraceae) against adult Schistosoma mansoni worms.
Article in Molecules (Basel, Switzerland), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 95 citations in OpenAlex.
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- Essential Oils as Novel Anthelmintic Drug Candidates.Molecules (Basel, Switzerland) · 2022Review
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- Chemical Profile and Biological Activities of Essential Oil fromPharmaceuticals (Basel, Switzerland) · 2019Article
- Methanolic extract of Agerantum conyzoides exhibited toxicity and growth disruption activities against Anopheles gambiae sensu stricto and Anopheles arabiensis larvae.BMC complementary and alternative medicine · 2016Article
- Dose-response relationship in Schistosoma mansoni juvenile and adult stages following limonin treatment in experimentally infected mice.Parasitology research · 2016Article
- Lethal and Inhibitory Activities of Plant-Derived Essential Oils Against Bemisia tabaci Gennadius (Hemiptera: Aleyrodidae) Biotype B in Tomato.Neotropical entomology · 2016Article
- Antischistosomal activity of the terpene nerolidol.Molecules (Basel, Switzerland) · 2014Article
- Anthelmintic activity of crude extract and essential oil of Tanacetum vulgare (Asteraceae) against adult worms of Schistosoma mansoni.TheScientificWorldJournal · 2014Article
- Chemical composition, antioxidant, anti-inflammatory and anti-proliferative activities of essential oils of plants from Burkina Faso.PloS one · 2014Article
- Novel therapeutic and prevention approaches for schistosomiasis: review.Journal of advanced research · 2013Review
- Anthelmintic activity of carvacryl acetate against Schistosoma mansoni.Parasitology research · 2013Article
- Antioxidant, antibacterial and antischistosomal activities of extracts from Grateloupia livida (Harv). Yamada.PloS one · 2013Article
- In vitro efficacy of the essential oil of Piper cubeba L. (Piperaceae) against Schistosoma mansoni.Parasitology research · 2012Article
- In vitro schistosomicidal activity of some brazilian cerrado species and their isolated compounds.Evidence-based complementary and alternative medicine : eCAM · 2012Article
Corrections and comments
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Authors and funding
13 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The in vitro schistosomicidal effects of the essential oil of Ageratum conyzoides L. (Ac-EO) against adult worms of Schistosoma mansoni is reported in this paper. Concerning this activity, Ac-EO was considered to be active, but less effective than the positive control (praziquantel, PZQ) in terms of separation of coupled pairs, mortality, decrease in motor activity, and tegumental alterations. However, Ac-EO caused an interesting dose-dependent reduction in the number of eggs of S. mansoni. Precocene I (74.30%) and (E)-caryophyllene (14.23%) were identified as the two major constituents of Ac-EO. These compounds were tested individually and were found to be much less effective than Ac-EO and PZQ. A mixture of the two major compounds in a ratio similar to that found in the Ac-EO was also less effective than Ac-EO, thus revealing that there are no synergistic effects between these components. These results suggest that the essential oil of A. conyzoides is very promising for the development of new schistosomicidal agents.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.