ArticleBiophysical journal2011
Shear stress increases the residence time of adhesion of Pseudomonas aeruginosa.
Article in Biophysical journal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 80 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
80 citing papers in PubMed, 212 citations in OpenAlex.
- Flow-driven delivery boosts antibiotic effectiveness by overwhelming bacterial defenses.bioRxiv : the preprint server for biology · 2026Article
- Detoxification of host-relevant HbioRxiv : the preprint server for biology · 2026Article
- Article
- Acute high shear stress enhances fungal cell/substrate adhesion.Microbiology spectrum · 2026Article
- Different Cell Wall Compositions of ESKAPE Isolates on Glass Surfaces Impact Adhesion Adaptability to Dynamic Shear Stress.Microorganisms · 2026Article
- A shear-induced limit on bacterial surface adhesion in fluid flow.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Flow-induced bending of flagella restrictsmBio · 2026Article
- Cellular membrane protein MipA from E.coli Nissle 1917 protects against Salmonella infection.The ISME journal · 2026Article
- Reduction of bacterial colonization on buckling-induced wrinkled surfaces under fluid shear.Nature communications · 2026Article
- Sphincter-induced dynamic obstruction in a synthetic intersphincteric anal fistula model: a proof-of-concept fluid-structure interaction study.Frontiers in medicine · 2026Article
- Stress-hardening behaviour of biofilm streamers.Nature communications · 2025Article
- Microfluidics unveils role of gravity and shear stress on Pseudomonas fluorescens motility and biofilm growth.NPJ biofilms and microbiomes · 2025Article
- Review
- Advancements and Challenges in Modeling Mechanobiology in Intestinal Host-Microbiota Interaction.ACS applied materials & interfaces · 2025Review
- Shear flow patterns antimicrobial gradients across bacterial populations.Science advances · 2025Article
- Bacterial species with different nanocolony morphologies have distinct flow-dependent colonization behaviors.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Inoculum selection and hydraulic retention time impacts in a microbial fuel cell treating saline wastewater.Applied microbiology and biotechnology · 2025Article
- The Impact of Fluid Flow on Microbial Growth and Distribution in Food Processing Systems.Foods (Basel, Switzerland) · 2025Review
- Shear stress controls prokaryotic and eukaryotic biofilm communities together with EPS and metabolomic expression in a semi-controlled coastal environment in the NW Mediterranean Sea.Environmental microbiome · 2024Article
- Combining multiple stressors blocks bacterial migration and growth.Current biology : CB · 2024Article
20 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
Although ubiquitous, the processes by which bacteria colonize surfaces remain poorly understood. Here we report results for the influence of the wall shear stress on the early-stage adhesion of Pseudomonas aeruginosa PA14 on glass and polydimethylsiloxane surfaces. We use image analysis to measure the residence time of each adhering bacterium under flow. Our main finding is that, on either surface, the characteristic residence time of bacteria increases approximately linearly as the shear stress increases (∼0-3.5 Pa). To investigate this phenomenon, we used mutant strains defective in surface organelles (type I pili, type IV pili, or the flagellum) or extracellular matrix production. Our results show that, although these bacterial surface features influence the frequency of adhesion events and the early-stage detachment probability, none of them is responsible for the trend in the shear-enhanced adhesion time. These observations bring what we believe are new insights into the mechanism of bacterial attachment in shear flows, and suggest a role for other intrinsic features of the cell surface, or a dynamic cell response to shear stress.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.